We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Sekisui Diagnostics UK Ltd.

Download Mobile App




Hypertension Treatment Beneficial Irrespective of Baseline Blood Pressure

By HospiMedica International staff writers
Posted on 10 Jan 2016
Print article
Treatment to lower blood pressure (BP) levels reduces the risk of major cardiovascular disease (CVD) events regardless of initial BP, according to a new study.

Researcher at the University of Oxford (United Kingdom), the University of Sydney (Australia), and other institutions affiliated with the George Institute for Global Health (Sydney, Australia) conducted a systematic review and meta-analysis of large-scale BP lowering trials published between Jan 1, 1966, and July 7, 2015. In all, a total of 123 studies with a minimum of 1,000 patient-years of follow-up were included, involving 613,815 participants.

The results showed that every 10 mmHg reduction in systolic BP significantly reduced the risk of major CVD events, coronary heart disease (CHD), stroke, and heart failure. In trials with higher and lower mean baseline systolic BP, similar proportional risk reductions were observed, with an overall 13% reduction in all-cause mortality; the effect on renal failure, however, was not significant. The researchers found no clear evidence for variation in proportional risk reduction in major CVD based on baseline disease history, with the exception of diabetes and chronic kidney disease (CKD), which correlated with smaller risk reductions.

From a disease management point of view, different classes of drugs to treat BP showed varying effects. For example, β-blockers were found to be inferior for the prevention of major CVD events, stroke, and renal failure, while calcium channel blockers were superior to other drugs for stroke prevention. But for the prevention of heart failure, calcium channel blockers were found to be inferior, while diuretics were superior to other drug classes. The study was published on December 23, 2015, in the Lancet.

“Blood pressure lowering significantly reduces vascular risk across various baseline levels and co-morbidities,” concluded lead author Dena Ettehad, MSc, of Oxford University, and colleagues of the George Institute for Global Health. “Our results provide strong support for lowering blood pressure to systolic blood pressures less than 130 mmHg and providing blood pressure lowering treatment to individuals with a history of cardiovascular disease, coronary heart disease, stroke, diabetes, heart failure, and chronic kidney disease.”

Related Links:

University of Oxford
University of Sydney
George Institute for Global Health


Gold Member
STI Test
Vivalytic Sexually Transmitted Infection (STI) Array
Gold Member
12-Channel ECG
CM1200B
Silver Member
Compact 14-Day Uninterrupted Holter ECG
NR-314P
New
Neonatal Transport Ventilator
Babylite

Print article

Channels

Surgical Techniques

view channel
Image: Lightning Flash 2.0 features advanced computer assisted vacuum thrombectomy software (Photo courtesy of Penumbra)

Next-Gen Computer Assisted Vacuum Thrombectomy Technology Rapidly Removes Blood Clots

Pulmonary embolism (PE) occurs when a blood clot blocks one of the arteries in the lungs. Often, these clots originate from the leg or another part of the body, a condition known as deep vein thrombosis,... Read more

Patient Care

view channel
Image: The newly-launched solution can transform operating room scheduling and boost utilization rates (Photo courtesy of Fujitsu)

Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization

An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The Quantra Hemostasis System has received US FDA special 510(k) clearance for use with its Quantra QStat Cartridge (Photo courtesy of HemoSonics)

Critical Bleeding Management System to Help Hospitals Further Standardize Viscoelastic Testing

Surgical procedures are often accompanied by significant blood loss and the subsequent high likelihood of the need for allogeneic blood transfusions. These transfusions, while critical, are linked to various... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.