Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
KOREA E & EX

Events

18 Feb 2016 - 20 Feb 2016
24 Feb 2016 - 26 Feb 2016

Pill Colors Play a Role in Medication Adherence

By HospiMedica International staff writers
Posted on 17 Jan 2013
Print article
Changes in pill color increase the risk that patients will not complete their antiepileptic drug (AED) prescriptions, according to a new study.

Researchers at Brigham and Women's Hospital (Boston, MA, USA) designed a nested case-control study involving 11,472 patients who failed to refill a prescription for an AED within 5 days of the time they ran out of pills; the controls, 50,050 patients, had no refill delays and were matched to cases by sex, age, number of refills, and the presence of a seizure disorder diagnosis. The researchers evaluated the two refills preceding nonpersistence, and compared the odds of discordance among cases and controls. In all, the drugs dispensed had 37 colors and four shapes.

The researchers found that color discordance preceded 136 cases (1.2%) but only 480 controls (0.97%); shape discordance preceded 18 cases (0.16%) and 54 controls (0.11%). Within a seizure disorder-diagnosis subgroup, the risk of nonpersistence after changes in pill color was also significantly elevated. The researchers concluded that changes in pill color significantly increase the odds of nonpersistence, and urge a reconsideration of current regulatory policy that permits wide variation in the appearance of bioequivalent drugs. The study was published on December 31, 2012, in Archives of Internal Medicine.

“A patient taking five medicines, each produced by five generic manufacturers, theoretically faces over 3,000 possible arrays of pill appearances for what are, chemically and clinically speaking, the same drugs,” said lead author Aaron Kesselheim, MD, JD. “Those choices could confuse patients and result in poor adherence to therapy.”

“Subjecting patients to this risk is absolutely senseless and absurd. Generic medicines should be required to look like their brand-name counterparts,” commented Archives of Internal Medicine associate Editor Kenneth Covinsky, MD. “With all the hurdles patients face, how on earth can we justify confusing them by needlessly changing the appearance of their medicines?”

Related Links:
Brigham and Women's Hospital


Print article
LevMed LTD.

Channels

Surgical Techniques

view channel

Nerve Cap Facilitates Management of Symptomatic Neuromas

An innovative device reduces painful neuroma formation, facilitating tissue repair and regeneration following nerve resection. Neurocap is a transparent tubular bioresorbable polymer cap that serves as a synthetic nerve covering. It was designed to help treat symptomatic neuromas by isolating the nerve stump from surrounding... Read more

Women's Health

view channel
Image: The Eclipse vaginal insert in deflated (L) and Inflated (R) states (Phoyo courtesy of Pelvalon).

Vaginal Insert Offers Alternative Treatment for Fecal Incontinence

A novel vaginal insert for bowel control eliminates the need for surgery or an in-office procedure for the treatment of female fecal incontinence (FI). The second-generation Eclipse System is comprised... Read more

Health IT

view channel
Image: The sweat sensor in a prototype flexible plastic wristband (Photo courtesy of Wei Gao et al., Nature).

Wearable Sensor Could Monitor Dehydration and Fatigue

A fully integrated electronic system that can continuously monitor multiple sweat chemicals could be incorporated into wristbands and headbands, according to a new study. The prototype device, developed... Read more

Hospital News

view channel

Geneia Partners with Hospitals on Population Health Training

Geneia (Harrisburg, PA, USA) will provide population health management training to members of the Illinois Health and Hospital Association (IHA; Chicago, USA). Through its education arm, The Geneia Institute, skills-based population health management programs will be delivered to IHA's 209 hospital and nearly 50 health... Read more

Business

view channel

Sentry Data Systems Buys Agilum Healthcare

Sentry Data Systems (Deerfield Beach, FL, USA), a provider of technology solutions for healthcare organizations, has completed the acquisition of Agilum Healthcare Intelligence (Brentwood, TN, USA). The acquisition is intended to add new capabilities to Sentry's current software-as-a-service (SaaS) DataNext healthcare... Read more
Copyright © 2000-2016 Globetech Media. All rights reserved.