Features | Partner Sites | Information | LinkXpress
Sign In
SOREDEX
Shuenn Bao Shing Corporation
Ampronix

Pill Colors Play a Role in Medication Adherence

By HospiMedica International staff writers
Posted on 17 Jan 2013
Changes in pill color increase the risk that patients will not complete their antiepileptic drug (AED) prescriptions, according to a new study.

Researchers at Brigham and Women's Hospital (Boston, MA, USA) designed a nested case-control study involving 11,472 patients who failed to refill a prescription for an AED within 5 days of the time they ran out of pills; the controls, 50,050 patients, had no refill delays and were matched to cases by sex, age, number of refills, and the presence of a seizure disorder diagnosis. The researchers evaluated the two refills preceding nonpersistence, and compared the odds of discordance among cases and controls. In all, the drugs dispensed had 37 colors and four shapes.

The researchers found that color discordance preceded 136 cases (1.2%) but only 480 controls (0.97%); shape discordance preceded 18 cases (0.16%) and 54 controls (0.11%). Within a seizure disorder-diagnosis subgroup, the risk of nonpersistence after changes in pill color was also significantly elevated. The researchers concluded that changes in pill color significantly increase the odds of nonpersistence, and urge a reconsideration of current regulatory policy that permits wide variation in the appearance of bioequivalent drugs. The study was published on December 31, 2012, in Archives of Internal Medicine.

“A patient taking five medicines, each produced by five generic manufacturers, theoretically faces over 3,000 possible arrays of pill appearances for what are, chemically and clinically speaking, the same drugs,” said lead author Aaron Kesselheim, MD, JD. “Those choices could confuse patients and result in poor adherence to therapy.”

“Subjecting patients to this risk is absolutely senseless and absurd. Generic medicines should be required to look like their brand-name counterparts,” commented Archives of Internal Medicine associate Editor Kenneth Covinsky, MD. “With all the hurdles patients face, how on earth can we justify confusing them by needlessly changing the appearance of their medicines?”

Related Links:
Brigham and Women's Hospital


CardioComm Solutions
Armstrong Medical Industries
Asian Healthcare Show

Channels

Critical Care

view channel

CDC Proposes the Counseling of all Males on Circumcision

The US Centers for Disease Control and Prevention (CDC; Atlanta, GA, USA) is recommending that doctors counsel parents of baby boys and teenagers, as well as men, on the benefits and risks of circumcision. The CDC's proposal opens the door to circumcision becoming a topic of conversation any time an uncircumcised male,... Read more

Women's Health

view channel

Women with PTSD Face Higher Pregnancy Risk

Suffering from post-traumatic stress disorder (PTSD) significantly increases a pregnant woman's risk of premature birth, according to a new study. Researchers at Stanford University (CA, USA) conducted a study to identify antenatal PTSD status and spontaneous preterm delivery in a retrospective cohort (2000-2012).... Read more

Health IT

view channel
Image: A screenshot from the 'cat and mouse' game designed to treat amblyopia (Photo courtesy of Ohio State University).

Video Games Help Improve Vision Training

New video games add an important element of entertainment to the repetitive training needed to improve vision in people with ambylopia (lazy eye) and poor depth perception. Developed by researchers... Read more

Hospital News

view channel
Image: Proposed site of the new University of Canberra Public Hospital (Photo courtesy of ACT).

New Hospital Planned at the University of Canberra

The government of the Australian Capital Territory (ACT, Canberra, Australia) has signed an agreement with University of Canberra (UC; Australia) to build a new hospital on its campus. The new UC Public... Read more

Business

view channel

Staff Shortages Driving Patient Monitoring Device Sector

Staff shortages and reductions are driving sales of patient monitoring systems with remote or wireless reporting functions. These are the latest findings of Kalorama Information (New York, NY, USA), an independent medical market research firm. While patient monitoring includes all products and services that facilitate... Read more
 
Copyright © 2000-2014 Globetech Media. All rights reserved.