Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Ampronix

Events

05 May 2016 - 07 May 2016
11 May 2016 - 14 May 2016

Drinking a Morning Colonoscopy Preparation Solution Leaves the Bowels Cleaner

By HospiMedica International staff writers
Posted on 28 Jul 2010
Print article
A new study suggests that having patients drink a polyethylene glycol (PEG) preparation solution the same morning (rather than the evening before) results in better bowel cleansing prior to afternoon colonoscopies.

Researchers at the Cleveland Clinic Florida (Weston, USA) conducted a prospective, randomized, endoscopist-blinded study examining the efficacy of bowel cleansing achieved by administering four liters of PEG preparation to 136 patients (mean age 51.8 years, 52.2% men) in the morning of an afternoon colonoscopy, compared to that of the traditional evening regimen. Patients were randomly assigned to drink the solution between 5-9 PM the evening before colonoscopy, or to drink the solution between 6-10 AM the same day of the procedure; they were allowed to eat breakfast the day before, followed by clear liquids for the rest of the day. Bowel cleansing efficacy was scored by a blinded endoscopist using the Ottawa scale, and each participant filled out a satisfaction survey. Mean scores for each bowel segment, composite mean scores, and rates of good preparation were compared between the two groups.

The results showed that patients in the morning group had significantly lower Ottawa scale scores and were more likely to have a good preparation for each bowel segment separately and overall when compared with the evening group; specifically, the right, middle, and left colon in the morning group were 3, 8, and 3 times more likely, respectively, to have a good preparation than the evening group. Moreover, patients in the morning group were over 50% less likely to lose sleep or have bloating compared with the evening group. There was no difference in the study groups on overall polyp detection rate, adenomatous polyps, or number of patients with adenomas. The study was published online in the July 6, 2010, issue of the American Journal of Gastroenterology.

"One reason why the morning bowel prep results in better cleansing is that as the patient finishes drinking the solution, bile starts to accumulate in the colon, staining the bowel so the colonoscopist can see less,” said lead author Fernando Castro, M.D., of the department of medicine and geriatrics. "The closer the colonoscopy to the time of the prep, the better the visibility is.”

PEG has a low toxicity and is the basis of a number of laxatives, skin creams, and sexual lubricants, frequently combined with glycerin. In whole bowel irrigation, PEG is used in conjunction with added electrolytes for bowel preparation before surgery, colonoscopy, and in treating drug overdoses.

Related Links:

Cleveland Clinic Florida




Print article
Radcal
Barco

Channels

Critical Care

view channel
Image: The new sensor device (L) and a cross-sectional scanning electron microscope photo of the copper(I)-bromide film (Photo courtesy of Fujitsu Laboratories).

Breath Sensor Measures Exhaled Gas Components

A portable breath sensor can measure the concentration of specified gas components correlated with lifestyle diseases such as high blood pressure, diabetes, and cancer. The sensor, developed at Fujitsu... Read more

Women's Health

view channel

Flu Shot During Pregnancy May Halve Stillbirth Risk

A new study suggests that seasonal trivalent influenza vaccination (TIV) during pregnancy is associated with a significant reduction in stillbirths. Researchers at the University of Western Australia (UWA; Crawley, Australia) and Emory University (Atlanta, GA, USA) conducted a large, population-based study to evaluate... Read more

Hospital News

view channel

Mikkeli Central Hospital to Undergo Major Modernization

The European Investment Bank (Luxemburg; EIB) has provided a long-term loan of € 55 million to the South Savo Social and Health Care Joint Authority to renovate and extend the Central Hospital campus in Mikkeli (Finland). The campus, situated in the center of the 55,000 municipality, will undergo a renovation and extension... Read more

Business

view channel

Mobility Aids Equipment Market to Experience Rapid Growth

The global market for mobility aids and transportation equipment market is estimated to reach USD 7.8 billion by 2021. These are the latest findings of IndustryARC (Hyderabad, India), an international research and consulting firm. Mobility equipment for the incapacitated, disabled and seniors is comprised of a large... Read more
Copyright © 2000-2016 Globetech Media. All rights reserved.