Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
KOREA E & EX

Events

18 Feb 2016 - 20 Feb 2016
24 Feb 2016 - 26 Feb 2016

Hip Implants More Likely to Fail in Women

By HospiMedica International staff writers
Posted on 06 Mar 2013
Print article
A new study indicates that patient gender is important for patient management and device selection in total hip arthroplasty (THA) procedures.

Researchers at the Southern California Kaiser Permanente Research Group (San Diego, USA) reviewed the Kaiser Permanente system's registry of total joint replacements performed at 46 hospitals in California, Hawaii, Oregon, Washington, and Colorado by 319 different surgeons between 2001 and 2010. The data included arthroplasty procedure volumes; the patients and the implants they received (cemented, uncemented, or hybrid); and implant bearing surface, such as metal on metal, metal or ceramic on highly crosslinked polyethylene, or ceramic on ceramic. Only patients undergoing unilateral procedures were included in the analysis.

In all, about 58% of the 35,140 procedures were performed in women (mean age 65.7, versus 63.8 for men). The age difference between men and women was statistically significant, and women in the cohort tended to be slightly more likely to be white or Asian and to have osteoarthritis (OA), rheumatoid arthritis (RA), or dysplasia. They were less likely to be diabetic or obese and to have osteonecrosis or post-traumatic arthritis. The main outcome measures were failure of THA, defined as revision procedure for any reason, septic reason, or aseptic reason after the index procedure.

The results showed that failure rates for hip implants were 29% higher for women than men, after controlling for a variety of factors including device type; the risk appeared most prominent for aseptic revision compared with septic failure. Larger femoral head sizes appeared especially problematic for women. For head sizes of 36 mm or more, the failure rate in women was 49% higher. Not surprisingly, women were much less likely to have implant femoral head sizes of 36 mm or more (32.8% versus 55.4% for men).

The researchers also found that much of the increased risk for women seemed concentrated in metal-on-metal implants, with a doubling in risk for women versus men (19.4% versus 9.6%). Overall, however, ceramic or metal on highly cross-linked polyethylene were more popular for female patients. The DePuy resurfacing implant was used in 1.3% of women versus 2.6% of men. The study was published on February 18, 2013, in JAMA Internal Medicine.

“After considering patient-, surgery-, surgeon-, volume-, and implant-specific risk factors, women had a 29% higher risk of implant failure than men after THA,” concluded lead author Maria Inacio, MS, and colleagues. “With no significant increase in risk of septic failure for women, the results mean that factors other than infection are responsible for the higher overall revision rate.”

Related Links:

Kaiser Permanente Research Group



Print article
LevMed LTD.

Channels

Women's Health

view channel
Image: The Eclipse vaginal insert in deflated (L) and Inflated (R) states (Phoyo courtesy of Pelvalon).

Vaginal Insert Offers Alternative Treatment for Fecal Incontinence

A novel vaginal insert for bowel control eliminates the need for surgery or an in-office procedure for the treatment of female fecal incontinence (FI). The second-generation Eclipse System is comprised... Read more

Health IT

view channel
Image: The sweat sensor in a prototype flexible plastic wristband (Photo courtesy of Wei Gao et al., Nature).

Wearable Sensor Could Monitor Dehydration and Fatigue

A fully integrated electronic system that can continuously monitor multiple sweat chemicals could be incorporated into wristbands and headbands, according to a new study. The prototype device, developed... Read more

Hospital News

view channel

Geneia Partners with Hospitals on Population Health Training

Geneia (Harrisburg, PA, USA) will provide population health management training to members of the Illinois Health and Hospital Association (IHA; Chicago, USA). Through its education arm, The Geneia Institute, skills-based population health management programs will be delivered to IHA's 209 hospital and nearly 50 health... Read more

Business

view channel

Sentry Data Systems Buys Agilum Healthcare

Sentry Data Systems (Deerfield Beach, FL, USA), a provider of technology solutions for healthcare organizations, has completed the acquisition of Agilum Healthcare Intelligence (Brentwood, TN, USA). The acquisition is intended to add new capabilities to Sentry's current software-as-a-service (SaaS) DataNext healthcare... Read more
Copyright © 2000-2016 Globetech Media. All rights reserved.