Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
KOREA E & EX

Events

18 Feb 2016 - 20 Feb 2016
24 Feb 2016 - 26 Feb 2016

Special Glasses Help Surgeons Visualize Cancer

By HospiMedica International staff writers
Posted on 27 Feb 2014
Print article
Image: Breast surgeon Julie Margenthaler, MD, visualizing cancer cells (Photo courtesy of WUSTL - Washington University in St. Louis).
Image: Breast surgeon Julie Margenthaler, MD, visualizing cancer cells (Photo courtesy of WUSTL - Washington University in St. Louis).
High-tech glasses may help surgeons distinguish cancer cells from healthy cells by making them glow blue when viewed through the eyewear.

Developed by researchers at Washington University (St. Louis, MO, USA), the technology, called optical projection of acquired luminescence (OPAL), incorporates custom video technology, a head-mounted display, and a targeted molecular contrast agent that attaches to cancer cells, making them glow blue when irradiated with a special light. The resulting fluorescence intensity maps are projected onto the imaged surface and viewed through the glasses, rather than via wall-mounted display monitors.

To demonstrate the proof-of-principle for OPAL applications in oncologic surgery, lymphatic transport of indocyanine green was visualized in live mice for real-time identification of sentinel lymph nodes. Subsequently, peritoneal tumors in a murine model of breast cancer metastasis were identified using OPAL following systemic administration of a tumor-selective fluorescent molecular probe. The researchers noted that tumors as small as one mm in diameter could be detected. The study was published in the December 2013 issue of the Journal of Biomedical Optics.

“These initial results clearly show that OPAL can enhance adoption and ease-of-use of fluorescence imaging in oncologic procedures relative to existing state-of-the-art intraoperative imaging systems,” said lead author professor of radiology and biomedical engineering Samuel Achilefu, PhD. “This technology has great potential for patients and health-care professionals. Our goal is to make sure no cancer is left behind.”

“We’re in the early stages of this technology, and more development and testing will be done, but we’re certainly encouraged by the potential benefits to patients,” said associate professor of surgery Julie Margenthaler, MD, who performed the first in-human operation using the system at the WUSTL Barnes-Jewish Hospital (St. Louis, MO, USA) on February 10, 2014. “Imagine what it would mean if these glasses eliminated the need for follow-up surgery and the associated pain, inconvenience, and anxiety.”

Related Links:

Washington University
Barnes-Jewish Hospital



Print article
LevMed LTD.

Channels

Women's Health

view channel
Image: The Eclipse vaginal insert in deflated (L) and Inflated (R) states (Phoyo courtesy of Pelvalon).

Vaginal Insert Offers Alternative Treatment for Fecal Incontinence

A novel vaginal insert for bowel control eliminates the need for surgery or an in-office procedure for the treatment of female fecal incontinence (FI). The second-generation Eclipse System is comprised... Read more

Health IT

view channel
Image: The sweat sensor in a prototype flexible plastic wristband (Photo courtesy of Wei Gao et al., Nature).

Wearable Sensor Could Monitor Dehydration and Fatigue

A fully integrated electronic system that can continuously monitor multiple sweat chemicals could be incorporated into wristbands and headbands, according to a new study. The prototype device, developed... Read more

Hospital News

view channel

Geneia Partners with Hospitals on Population Health Training

Geneia (Harrisburg, PA, USA) will provide population health management training to members of the Illinois Health and Hospital Association (IHA; Chicago, USA). Through its education arm, The Geneia Institute, skills-based population health management programs will be delivered to IHA's 209 hospital and nearly 50 health... Read more

Business

view channel

Sentry Data Systems Buys Agilum Healthcare

Sentry Data Systems (Deerfield Beach, FL, USA), a provider of technology solutions for healthcare organizations, has completed the acquisition of Agilum Healthcare Intelligence (Brentwood, TN, USA). The acquisition is intended to add new capabilities to Sentry's current software-as-a-service (SaaS) DataNext healthcare... Read more
Copyright © 2000-2016 Globetech Media. All rights reserved.