We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App




Transplant Patients Suffer More Mohs Surgery Infections

By HospiMedica International staff writers
Posted on 21 Mar 2017
Print article
Image
Image
Patients with a history of immunosuppression (IS) who undergo Mohs micrographic surgery (MMS) are more likely to experience post-surgical complications, according to a new study.

Researchers at the University of California, San Diego conducted a cross-sectional retrospective study that included data involving 4,151 patients who underwent MMS for non-melanoma skin cancer (NMSC); of these, 693 patients were defined as IS, including patients who were solid organ transplant recipients (SOTR), patients on chronic immunosuppressive therapy, or patients who had a diagnosis of leukemia, lymphoma, or HIV. Complication was defined as any adverse event reported within two weeks of MMS, directly related to the procedure.

The result showed that overall IS status was associated with a 9.6 times odds of complication. Among subtypes, SOTR had 8.824 times the odds of complication, while hematologic malignancy or HIV-positive status did not predict significantly higher odds. IS therapy was associated with 5.775 times the odds of complication, with the macrolides sirolimus and tacrolimus displaying 18 and 9 times higher odds, respectively. The study was presented as a poster session at the annual meeting of the American Academy of Dermatology, held during March 2017 in Orlando (FL, USA).

“IS patients are not only at higher risk for multiple, aggressive NMSCs, but may be at increased risk for overall post-operative complication following MMS,” concluded lead author UCSD medical student Pallavi Basu, BA, and colleagues. “In particular, heart transplant recipients or patients on sirolimus or tacrolimus may benefit from post-procedure infection prophylaxis, as well as careful management and repair to avoid necrosis or hematoma.”

MMS is the treatment of choice for basal cell and squamous cell carcinomas at high risk for local recurrence. The technique involves removal of the cutaneous carcinomas using precise microscopic marginal control with the aid of horizontal frozen sections. Advantages include superior cure rates, maximal tissue conservation, the ability to trace perineural or infiltrating tumors histologically, overall lower costs relative to that of radiation therapy, excision, or surgery, and negligible risk of complications from general anesthesia.

Gold Member
POC Blood Gas Analyzer
Stat Profile Prime Plus
Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Silver Member
Wireless Mobile ECG Recorder
NR-1207-3/NR-1207-E
New
Infant Blood Draw Station
Infant Blood Draw Station

Print article

Channels

Surgical Techniques

view channel
Image: NTT and Olympus have begun the world\'s first joint demonstration experiment of a cloud endoscopy system (Photo courtesy of Olympus)

Cloud Endoscopy System Enables Real-Time Image Processing on the Cloud

Endoscopes, which are flexible tubes inserted into the body's natural openings for internal examination and biopsy collection, are becoming increasingly vital in medical diagnostics. Their minimal invasiveness... Read more

Patient Care

view channel
Image: The newly-launched solution can transform operating room scheduling and boost utilization rates (Photo courtesy of Fujitsu)

Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization

An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The PATHFAST hs-cTnI-II high-sensitivity troponin assay has been developed for the PATHFAST Biomarker Analyzer (Photo courtesy of Polymedco)

POC Myocardial Infarction Test Delivers Results in 17 Minutes

Chest pain is the second leading cause of emergency department (ED) visits by adults in the United States, generating over 7 million visits annually. In the event of a suspected heart attack, physicians... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.