We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Portable Extracorporeal System Preserves Organs for Transplantation

By HospiMedica International staff writers
Posted on 13 Oct 2021
Print article
Image: The TransMedics Organ Care System (OCS) (Photo courtesy of Transmedics)
Image: The TransMedics Organ Care System (OCS) (Photo courtesy of Transmedics)
Innovative technology preserves and assesses livers, hearts, and lungs from donors following brain death (DBD) and after circulatory death (DCD).

The TransMedics (Andover, MA, USA) Organ Care System (OCS) is designed to maintain donor organs in near physiologic and functioning state outside of the human body, from the time the organ is removed from the donor, and until it is ready to be transplanted into a suitable recipient. The system works by perfusing the organ with warm oxygenated blood to minimize cold ischemia injury; optimizing the organ by replenishing oxygen, nutrients, and hormones that would otherwise become depleted; and providing continuous monitoring and assessment of the organ until the point of transplantation.

The system consists of a console, a reusable, portable enclosure that houses an electronic display and the non-sterile mechanical and electrical elements required to warm, pump, and ventilate the organ; a perfusion module, with an organ chamber and circulatory system to perfuse the organ; and a high oncotic solution for ex-vivo flushing and perfusion of the organ, when combined with packed red blood cells (pRBCs). The technology can increase the pool of current donor organs, improve patient survival, and reduce post-transplant complications.

“I am convinced that broad availability of warm extracoporeal donor liver perfusion will be the most important advance for the field of liver transplantation in decades,” said James Markmann, MD, chief of the division of transplantation surgery at Massachusetts General Hospital (Boston, USA). “OCS Liver has the potential to save many lives by making liver transplants safer and by expanding the pool of available liver allografts.”

The cornerstone of organ preservation has long been cold ischemic storage. Although this method is intended to reduce the extent of organ damage during transport, significant deterioration of the donated organ still occurs; the longer the organ is kept on ice, the greater the damage. Moreover, the cold storage technique does not enable any resuscitative or assessment while the organ is being transported from donor to recipient. It is estimated that 60-65% of organs cannot ultimately be used for transplantation due to the limitations of cold storage.

Related Links:

Print article
IIR Middle East


Surgical Techniques

view channel
Image: Engineers have developed a process that enables soft robots to grow like plants (Photo courtesy of University of Minnesota)

Soft Robotic System Can Grow Like Plants to Allow Surgical Access to Hard-To-Reach Areas

Soft robotics is an emerging field where robots are made of soft, pliable materials as opposed to rigid ones. Soft growing robots can create new material and “grow” as they move. These machines could be... Read more

Patient Care

view channel
Image: The biomolecular film can be picked up with tweezers and placed onto a wound (Photo courtesy of TUM)

Biomolecular Wound Healing Film Adheres to Sensitive Tissue and Releases Active Ingredients

Conventional bandages may be very effective for treating smaller skin abrasions, but things get more difficult when it comes to soft-tissue injuries such as on the tongue or on sensitive surfaces like... Read more

Health IT

view channel
Image: Using digital data can improve health outcomes (Photo courtesy of Unsplash)

Electronic Health Records May Be Key to Improving Patient Care, Study Finds

When a patient gets transferred from a hospital to a nearby specialist or rehabilitation facility, it is often difficult for personnel at the new facility to access the patient’s electronic health records... Read more


view channel
Image: Differentiated stapling technology for bariatric surgery (Photo courtesy of Standard Bariatrics)

Teleflex Completes Acquisition of Bariatric Stapling Technology Innovator

Teleflex Incorporated (Wayne, PA, USA), a leading global provider of medical technologies, has completed the previously announced acquisition of Standard Bariatrics, Inc. (Cincinnati, OH, USA), which has... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.