We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us


Develops, manufactures and markets rapid diagnostic tests at the point-ofcare (POC) that focus on infectious diseases... read more Featured Products: More products

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Quidel Triage Cardiac Panel Facilitates Rapid POC Diagnosis of Chest Pain Patients in ED

By HospiMedica International staff writers
Posted on 17 May 2022
Print article
Image: Triage Cardiac Panel is a rapid, POC fluorescence immunoassay used with Triage MeterPro (Photo courtesy of Quidel)
Image: Triage Cardiac Panel is a rapid, POC fluorescence immunoassay used with Triage MeterPro (Photo courtesy of Quidel)

Chest and abdominal pain are the most common reasons that persons aged 15 years and over visit the emergency department (ED). Because both emergency and non-emergency care are provided, symptoms vary widely in their acuity. The ECG is often non-diagnostic with a sensitivity of less than 60%. Atypical symptoms often seen in the elderly, women, and patients with diabetes make the clinical diagnosis even more difficult. Prolonged laboratory results may delay recognition of critically ill patients and initiation of appropriate therapies. It has been shown that quicker treatment times are associated with improved patient outcomes due to an earlier diagnosis. A point-of-care (POC), serial multi-marker testing strategy has been shown to facilitate the rapid diagnosis and management of chest pain patients in the ED.

Quidel Corporation (San Diego, CA, USA) has developed the Triage Cardiac Panel for use in the ED that is FDA cleared to aid in the diagnosis of myocardial infarction. The Quidel Triage Cardiac Panel is a rapid, point of care fluorescence immunoassay used with the Quidel Triage MeterPro. The test is designed to determine the level of creatine kinase MB (CK-MB), myoglobin and troponin I in EDTA anticoagulated whole blood or plasma specimens. This can be used as an aid in the diagnosis of myocardial infarction (injury).

At discharge, it is estimated that as many as 85% of chest pain patients do not have a cardiac diagnosis and myocardial infarction was missed in 2% - 8%. The Quidel Triage Cardiac Panel’s POC multi marker strategy provides meaningful diagnostic information to differentiate acute myocardial infarction (AMI) from other cardiac abnormalities. It has a near perfect NPV (99.9%) that allows for rapid rule out and the potential to decrease ED Length Of Stay (LOS) and turnaround time (TAT). It also has the potential to increase the number of stays less than 24 hours (decreases unnecessary admissions), thereby improving clinical, economic and operational outcomes. The test uses plasma or whole blood samples in EDTA and has time to results of about 20 minutes.

A 2008 retrospective analysis from three HCA hospitals tested chest pain patients using the Quidel Triage Cardiac Panel at one to three hour intervals. Rule-in criteria were (1) any TnI above the AMI cutoff on any draw; (2) a 50% increase in myoglobin levels with any detectable TnI on the last draw; or (3) a 50% increase in myoglobin with a concomitant increase in CKMB. In the retrospective study, most patients were safely evaluated and dispositioned in three hours or less. In the same three-hour window, rule-in patients were identified with a clinical sensitivity of 98.1%. Specificity was 98.1%; accuracy 99.7%; the PPV (positive predictive value) was 92.6%, and the NPV (negative predictive value) was 99.9%.

Additionally, a before and after study at a 567-bed teaching hospital demonstrated operational efficiencies gained by implementing the Quidel Triage Cardiac Panel with a zero, two and four hour protocol. The goal of the ED was to expedite the disposition of patients presenting with chest pain symptoms and move patients to the appropriate treatment pathway. The study demonstrated a reduction of 60 patients (36%) coded as DRG 143 (non-specific chest pain), freeing up needed beds in the ED. The average length of stay for the ED was shortened by 122 minutes (31%). Moreover, NSTEMI patients were ruled in more quickly with a 41% reduction in their length of stay.

Related Links:
Quidel Corporation 

Print article


Surgical Techniques

view channel
Image: The NaoTrac CE-certified neurosurgical navigation robot has received TFDA approval (Photo courtesy of Brain Navi Biotechnology)

Neurosurgical Navigation Robot Combines AI and Machine Vision to Streamline Procedures

Amidst the increasing demand for minimally invasive surgery, neuro-navigation has become standard in neurosurgery worldwide. Currently, most navigation systems use a “vision-based optical tracking system”... Read more

Patient Care

view channel
Image: The biomolecular film can be picked up with tweezers and placed onto a wound (Photo courtesy of TUM)

Biomolecular Wound Healing Film Adheres to Sensitive Tissue and Releases Active Ingredients

Conventional bandages may be very effective for treating smaller skin abrasions, but things get more difficult when it comes to soft-tissue injuries such as on the tongue or on sensitive surfaces like... Read more

Health IT

view channel
Image: AI can reveal a patient`s heart health (Photo courtesy of Mayo Clinic)

AI Trained for Specific Vocal Biomarkers Could Accurately Predict Coronary Artery Disease

Earlier studies have examined the use of voice analysis for identifying voice markers associated with coronary artery disease (CAD) and heart failure. Other research groups have explored the use of similar... Read more


view channel
Image: The global capsule endoscopy system market is growing at a rapid pace (Photo courtesy of Pexels)

Capsule Endoscopy System Market Driven by Rising Preference for Minimally Invasive Screening Procedure

Capsule endoscopy is generally a non-invasive technique that enables complete examination of the gastrointestinal tract with the use of the disposable and wireless device known as the video capsule.... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.