We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App





COVID-19 Vaccine Patch Fights SARS-CoV-2 Variants Better than Needles

By HospiMedica International staff writers
Posted on 03 Aug 2022
Print article
Image: Needle-free vaccine patch could better fight COVID-19 variants (Photo courtesy of University of Queensland)
Image: Needle-free vaccine patch could better fight COVID-19 variants (Photo courtesy of University of Queensland)

The ongoing SARS-CoV-2 pandemic continues to pose an enormous health challenge globally. The ongoing emergence of variants of concern has resulted in decreased vaccine efficacy necessitating booster immunizations. This was particularly highlighted by the recent emergence of the Omicron variant, which contains over 30 mutations in the spike protein and quickly became the dominant viral strain in global circulation. Currently-available vaccines may not be as effective because of the constantly emerging new variants of COVID-19, and this has left researchers at a crossroads. Now, a new study in mice suggests that a needle-free vaccine patch could better fight COVID-19 variants, such as Omicron and Delta, than a traditional needle vaccine.

The research, conducted by researchers at the University of Queensland (Brisbane, Australia), in partnership with Vaxxas (Brisbane, Australia), tested the Hexapro SARS-CoV-2 spike vaccine using the Vaxxas high-density microarray patch (HD-MAP) technology, and the results found the patch was far more effective at neutralizing COVID-19 variants. The researchers found that the vaccine patch appeared to counteract new variants more effectively than the current SARs-CoV-2 vaccine delivered by injection. The results extended further than just the Hexapro vaccine.

“The high-density microarray patch is a vaccine delivery platform that precisely delivers the vaccine into the layers of the skin which are rich in immune cells,” said UQ’s Dr Christopher McMillan. “We found that vaccination via a patch was approximately 11 times more effective at combatting the Omicron variant when compared with the same vaccine administered via a needle. So far, every vaccine type we have tested through the patch, including subunit, DNA, inactivated virus and conjugate produces superior immune responses compared to traditional needle vaccination methods.”

“The large number of mutations have given the virus the ability to evade the immune responses generated by the current vaccines,” said UQ’s Dr David Muller. “However, the patch technology has the potential to offer a new – and more effective – weapon in our arsenal, at a time where new variants are mutating at a rapid rate. The patches are not only more effective against emerging variants but are also far easier to administer than needle-based vaccines.”

Related Links:
University of Queensland 
Vaxxas 


Print article
IIR Middle East

Channels

Critical Care

view channel
Image: Three dimensional measurement of the all-mesh thermistor (Photo courtesy of Shinshu University)

Ultraflexible, Gas-Permeable Thermistors to Pave Way for On-Skin Medical Sensors and Implantable Devices

On-skin medical sensors and wearable health devices are important health care tools that must be incredibly flexible and ultrathin so they can move with the human body. In addition, the technology has... Read more

Surgical Techniques

view channel
Image: The POINT Kinguide robotic-assisted surgical system has made its debut in the US (Photo courtesy of Point Robotics)

First-Ever Spinal Surgical Hand-Held Robot Makes Worldwide Debut

The world’s first ever hand-held robot framework equipped with a parallel manipulator for orthopedic application has made its worldwide debut in the U.S. Point Robotics MedTech Inc. (Taipei, Taiwan) has... Read more

Patient Care

view channel
Image: The biomolecular film can be picked up with tweezers and placed onto a wound (Photo courtesy of TUM)

Biomolecular Wound Healing Film Adheres to Sensitive Tissue and Releases Active Ingredients

Conventional bandages may be very effective for treating smaller skin abrasions, but things get more difficult when it comes to soft-tissue injuries such as on the tongue or on sensitive surfaces like... Read more

Health IT

view channel
Image: Using digital data can improve health outcomes (Photo courtesy of Unsplash)

Electronic Health Records May Be Key to Improving Patient Care, Study Finds

When a patient gets transferred from a hospital to a nearby specialist or rehabilitation facility, it is often difficult for personnel at the new facility to access the patient’s electronic health records... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.