We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Thermo Fisher Scientific - Direct Effect Media

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Preterm Birth Linked to Increased Risk of Autism

By HospiMedica International staff writers
Posted on 31 Aug 2021
Print article
Image: Pre-term birth can lead to higher risk of ASD (Photo courtesy of CanStockPhoto)
Image: Pre-term birth can lead to higher risk of ASD (Photo courtesy of CanStockPhoto)
Preterm and early birth is associated with an increased risk of autism spectrum disorder (ASD), independent of genetic or environmental factors, according to a new study.

Researchers at Lund University (LU; Malmö, Sweden) and the Icahn School of Medicine at Mount Sinai (MSSM; New York, NY, USA) conducted a national cohort study that included all 4,061,795 singleton infants born in Sweden during 1973–2013 who survived to age one year, and who were followed-up for ASD, as identified from nationwide outpatient and inpatient diagnoses through 2015. The study wished to examine whether gestational age at birth was associated with ASD. Co-sibling analyses were used to assess the influence of unmeasured shared familial (genetic and/or environmental) factors.

The results showed that ASD prevalence, as reflected by gestational age at birth, were 6.1% for extremely preterm (22–27 weeks), 2.6% for very to moderate preterm (28–33 weeks), 1.9% for late preterm (34–36 weeks), 2.1% for all preterm (lower than 37 weeks), 1.6% for early term (37–38 weeks), and 1.4% for term (39–41 weeks) births. Adjusted prevalence ratios comparing extremely preterm, all preterm, or early term (versus term) were 3.72, 1.35, and 1.11 in boys, and 4.19, 1.53, and 1.16, among girls, respectively. These associations were only slightly offset after controlling for shared familial factors. The study was published in the August 2021 issue of Pediatrics.

“Children born prematurely need early evaluation and long-term follow-up to facilitate timely detection and treatment of autism, especially those born at the earliest gestational ages,” said lead author Casey Crump, MD, PhD, of MSSM. “More research is needed to understand the biologic mechanisms linking preterm birth with higher risks of autism. In patients of all ages, gestational age at birth should be routinely included in history-taking and medical records to help identify in clinical practice those born preterm or early term.”

ASD affects six per 1,000 children, and occurs more often among boys than girls. ASD affect three different areas of a child's life - social interaction, communication (both verbal and non-verbal), and behaviors and interests. The three main types are Asperger's syndrome, pervasive developmental disorder, not otherwise specified (PDD-NOS), and autistic disorder. The DSM -5 also included two rare but severe autistic-like conditions, called Rett syndrome and childhood disintegrative disorder.

Related Links:
Lund University
Icahn School of Medicine at Mount Sinai

Print article


Critical Care

view channel
Image: Triage Cardiac Panel is a rapid, POC fluorescence immunoassay used with Triage MeterPro (Photo courtesy of Quidel)

Quidel Triage Cardiac Panel Facilitates Rapid POC Diagnosis of Chest Pain Patients in ED

Chest and abdominal pain are the most common reasons that persons aged 15 years and over visit the emergency department (ED). Because both emergency and non-emergency care are provided, symptoms vary widely... Read more

Surgical Techniques

view channel
Image: Resolute Onyx DES helps address all DES needs and numerous patient anatomies (Photo courtesy of Medtronic)

Medtronic’s Latest Generation Drug-Eluting Coronary Stent System Offers Dual-Layer Balloon Technology

Coronary artery disease (CAD) is one of the leading causes of death and is caused by plaque buildup on the inside of the coronary arteries. These plaque deposits can narrow or clog the inside of the arteries,... Read more

Patient Care

view channel
Image: Future wearable health tech could measure gases released from skin (Photo courtesy of Pexels)

Wearable Health Tech Could Measure Gases Released From Skin to Monitor Metabolic Diseases

Most research on measuring human biomarkers, which are measures of a body’s health, rely on electrical signals to sense the chemicals excreted in sweat. But sensors that rely on perspiration often require... Read more

Health IT

view channel
Image: AI can reveal a patient`s heart health (Photo courtesy of Mayo Clinic)

AI Trained for Specific Vocal Biomarkers Could Accurately Predict Coronary Artery Disease

Earlier studies have examined the use of voice analysis for identifying voice markers associated with coronary artery disease (CAD) and heart failure. Other research groups have explored the use of similar... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.