Online Tool Assesses Osteoporotic Fracture Risk

FRAX, which is freely available for use online, was launched in February 2008. It was developed by Prof. John A. Kanis and colleagues from the WHO Collaborating Center for Metabolic Bone Diseases at the University of Sheffield Medical School (UK) and is underpinned by the World Health Organization (WHO; Geneva, Switzerland) Technical Report entitled "Assessment of Osteoporosis at Primary Health Care Level.”

The tool assesses the 10-year risk (absolute risk) of fracture of an individual, based on his/her clinical risk factors, which include an individual's age, sex, weight, height, prior fracture, parental history of hip fracture, smoking, long-term use of glucocorticoids, rheumatoid arthritis, and alcohol consumption. Although bone mineral density (BMD) is no longer the only criteria used to determine fracture risk, BMD values can be input into the calculation to better refine the accuracy of the result.

The great potential advantage of the tool is a better allocation of healthcare resources towards patients at higher risk of fracture. All risk factors are assessed depending on their relative risk for fracture, with, for example, age and low BMD being higher risk factors compared to alcohol consumption. The online tool provides easy access for the evaluation of a patient's fracture risk (hip and other osteoporotic fractures) and is of specific importance in countries where densitometry scans are not necessarily available.

Prof. Kanis commented, "The incorporation of the WHO Fracture Risk Assessment Tool into practice guidelines around the world will help improve patient management and avoid unnecessary treatment in men and women at low risk. I hope that the tool, which is freely available to all, will be adopted worldwide as the determination of fracture probability becomes more country-specific.”

The tool, previously available for China, France, Italy, Japan, Spain, Sweden, Turkey, United Kingdom, and the United States is now extended for use in Austria, Germany, and Switzerland. It is expected that FRAX will be available for several other countries before the end of 2009. With about 55,000 hits per day, FRAX is becoming a widely used tool in the clinical setting.

The FRAX tool has been integrated into new clinical guidelines for the management of osteoporosis in the United Kingdom and in the United States, and has also been adopted by the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis in new guidelines issued in 2008.

Related Links:
FRAX
World Health Organization