Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
Sekisui Diagnostics

Download Mobile App




Alliance to Develop New Cancer Diagnostic Tests

By HospiMedica staff writers
Posted on 14 Apr 2004
New diagnostic tests are to be developed that are based on the TRAIL receptor-1 (Trail-R1) and TRAIL Receptor-2 (TRAIL-2) proteins. More...
TRAIL is the acronym for tumor necrosis factor related apoptosis-inducing ligand.

The TRAIL receptors are found on the surface of a number of solid tumor and hematopoietic cancer cells, and they were discovered by researchers at Human Genome Sciences (HGS, Rockville, MD, USA). Worldwide exclusive rights to develop and commercialize diagnostic tests based on these proteins have been granted to DakoCytomation (Copenhagen, Denmark) by HGSI. According to an agreement with HGSI, DakoCytomation will be the exclusive partner of HGSI for any licensed immunohistochemical diagnostic product based on the TRAIL proteins.

HGSI intends to use experimental immunohistochemical tests developed by DakoCytomation in future clinical trials to explore the correlation between receptor expression and clinical response to treatment with TRAIL-1 or TRAIL-2 agonistic human monoclonal antibodies. DakoCytomation pioneered the concept of pharmacodiagnostics with HercepTest, the first clinical test that helped to assess candidates for a specific targeted therapy.

"The immunohistochemical tests under development as a result of the collaboration between our companies will play an important role in clinical trials in exploring the correlation between TRAIL Receptor-1 and TRAIL Receptor-2 expression and clinical response to treatment of various cancers with TRAIL-R1 and TRAIL-R2 agonistic human monoclonal antibodies,” said David C. Stump, M.D., executive vice president, drug development, HGSI.





Related Links:
HGSI
DakoCytomation

Gold Member
NEW PRODUCT : SILICONE WASHING MACHINE TRAY COVER WITH VICOLAB SILICONE NET VICOLAB®
REGISTRED 682.9
Radiology Monitor
MDNC-6121 Barco Nio Color 5.8MP
POC Respiratory/Sore Throat Test
BIOFIRE SPOTFIRE (R/ST) Panel
Multi-Chamber Washer-Disinfector
WD 390
Read the full article by registering today, it's FREE! It's Free!
Register now for FREE to HospiMedica.com and get access to news and events that shape the world of Hospital Medicine.
  • Free digital version edition of HospiMedica International sent by email on regular basis
  • Free print version of HospiMedica International magazine (available only outside USA and Canada).
  • Free and unlimited access to back issues of HospiMedica International in digital format
  • Free HospiMedica International Newsletter sent every week containing the latest news
  • Free breaking news sent via email
  • Free access to Events Calendar
  • Free access to LinkXpress new product services
  • REGISTRATION IS FREE AND EASY!
Click here to Register








Channels

Point of Care

view channel
Image Credit: 123RF

Continuous Glucose Monitoring Identifies Cardiometabolic Risk in Adults Without Diabetes

Dysglycemia—abnormal blood glucose regulation—can fluctuate throughout the day and often escape conventional screening. Clinicians typically rely on fasting plasma glucose and hemoglobin A1c, which offer... Read more

Business

view channel
Image: LigaSure RAS Maryland, designed for the Valleylab FT10 platform on Hugo RAS, seals and cuts vessels, tissue, and lymphatics up to 7 mm in diameter (Photo courtesy of Medtronic)

Medtronic Receives FDA Clearance for Vessel-Sealing Instrument for Robotic Surgery

As robotic-assisted surgery expands across U.S. hospitals, teams increasingly seek energy instruments with the familiarity and performance of tools used in open and laparoscopic procedures.... Read more
Copyright © 2000-2026 Globetech Media. All rights reserved.