We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
Radcal

Download Mobile App




Groundbreaking POCT Device Detects UTI Causing Bacteria in Five Minutes

By HospiMedica International staff writers
Posted on 17 Aug 2023
Print article
Image: A point-of-care aptasensor enables rapid diagnosis of UTIs (Photo courtesy of ACS Central Science, 2023)
Image: A point-of-care aptasensor enables rapid diagnosis of UTIs (Photo courtesy of ACS Central Science, 2023)

Urinary tract infection (UTI) is a prevalent health concern globally, particularly affecting women during pregnancy. Various bacteria can cause UTIs, leading to symptoms like a burning sensation during urination and an increased need to urinate. If the infection spreads to the kidneys, it can result in serious complications. Conventionally, urine cultures are used to detect and identify the specific bacteria responsible, a process that takes at least two days. This delay can cause suffering for the patient and even be fatal in some instances. In rural areas, the problem is exacerbated by inadequate infrastructure, high testing costs, and extended testing time, leading to many UTIs going undetected.

Researchers at the Indian Institute of Technology Guwahati (IIT Guwahati, Assam, India) have made a significant breakthrough by creating a 3D printed photodetector device that can identify and quantify a UTI-causing bacteria known as Klebsiella pneumoniae within five minutes from a urine sample. This capability is highly significant, as Klebsiella pneumoniae is not only a common cause of UTI but is also linked to pneumonia and soft tissue infections.

To create the prototype, the researchers utilized gold nanoparticles combined with specially engineered aptamers. An aptamer is similar to a 3D puzzle piece that fits only on the surface of specific bacteria. As a result, the gold nanoparticles get agglomerated on the surface of the target bacteria, generating a unique signature detectable by a UV-visible spectrophotometer. The device’s biosensor identifies changes in light intensity when the aptamer-gold nanoparticles-bacteria come together. The aptamer and bacteria combine instantly to result in rapid detection. Importantly, this innovative prototype is not only specific to Klebsiella pneumoniae but is also adaptable to different types of bacteria, offering great potential for primary healthcare. Furthermore, the cost-effective nature of the device could make it particularly beneficial in rural areas where UTIs frequently remain undiagnosed due to limited access to testing facilities.

Related Links:
IIT Guwahati 

Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Gold Member
12-Channel ECG
CM1200B
Silver Member
Wireless Mobile ECG Recorder
NR-1207-3/NR-1207-E
New
Silver Member
ECG Cart System
NECG Trolley

Print article

Channels

Critical Care

view channel
Image: The AI model uses data from patients\' electronic health records to predict their chances of surviving CRRT (Photo courtesy of 123RF)

AI Model Accurately Predicts Continuous Renal Replacement Therapy Survival

Continuous renal replacement therapy (CRRT) is a type of dialysis used for severely ill patients who are unable to undergo regular hemodialysis. Although CRRT has been in use for many decades, there is... Read more

Surgical Techniques

view channel
Image: Classification of the guidance image applied for surgical robot (Photo courtesy of Science China Press)

Advances in Image-Guided Methods Enabling Intelligent Surgical Robots for Precise Procedures

Traditional image-guided methods often depend on stationary equipment within the operating room, while modern surgical robots are equipped to acquire and process high-precision images in real time during surgeries.... Read more

Patient Care

view channel
Image: The portable, handheld BeamClean technology inactivates pathogens on commonly touched surfaces in seconds (Photo courtesy of Freestyle Partners)

First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds

Reducing healthcare-acquired infections (HAIs) remains a pressing issue within global healthcare systems. In the United States alone, 1.7 million patients contract HAIs annually, leading to approximately... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Business

view channel
Image: The finalists have been announced for the IHF Awards 2024 (Photo courtesy of IHF)

International Hospital Federation Awards 2024 Finalists Announced

The International Hospital Federation (IHF; Geneva, Switzerland) has announced the finalists of the IHF Awards 2024 after the judges completed scoring entries in all 7 Award categories. The IHF Awards... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.