Aspirin Hydrogels Provide Effective and Rapid Healing of Radiation Wounds

Radiation therapy, a common treatment for cancer, often leads to skin damage due to prolonged exposure. Individuals receiving radiation treatment typically suffer from skin injuries ranging from redness and pain to ulcers and infections. Current treatments for these injuries are limited and typically involve debridement (the surgical removal of dead tissue) or hyperbaric oxygen therapy (which involves breathing pure oxygen in a pressurized room). However, hydrogel-based wound dressings are becoming a favored alternative because they are simple to use and create a moist healing environment that mimics the body's own conditions. Hydrogels based on glycopeptides are particularly effective, having shown promise in laboratory and animal studies to enhance cellular growth and assist in cell adhesion and migration. Now, researchers have developed a hydrogel infused with aspirin, which simulates the nutrient-rich fluid found between cells, offering accelerated healing for radiation-damaged skin in animal models, suggesting it could be an efficient and rapid treatment for humans.

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