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Enhanced Stent Retriever Treats Ischemic Stroke

By HospiMedica International staff writers
Posted on 30 May 2018
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Image: The upgraded EmboTrap II stent retriever (Photo courtesy of Cerenovus).
Image: The upgraded EmboTrap II stent retriever (Photo courtesy of Cerenovus).
A next-generation stent retriever captures and removes life-threatening blood clots from the brain following an ischemic stroke.

The Cerenovus (Irvine, CA, USA) EmboTrap II revascularization device is intended to restore blood flow in the neurovasculature by removing thrombii in patients experiencing ischemic stroke within eight hours of symptom onset. The 0.021”, microcatheter compatible clot retriever is designed to trap blood clots with minimum compression, rapidly deliver thrombolysis in cerebral infarction (TICI) 2b-3 reperfusion therapy, and retain the clots during removal to protect the patient from distal embolisms.

The EmboTrap II, which is available in both 5×33 and 5×21 sizes, features an inner channel that allows bypass while open, and five chambers to improve the clot-device interaction. The device also has a distal section with an extensive mesh designed to keep the clot in place, so that it does not fragment. The analysis of revascularisation in ischemic stroke with EmboTrap (ARISE II) study showed a final procedural reperfusion rate of 92.5% among acute ischemic stroke patients with large vessel occlusion within three passes of the EmboTrap II.

“Embotrap II is the product of deep collaboration between engineers and clinicians to better understand the science of blood clot, what causes them to form and how a mechanical thrombectomy device can interact with them to help improve outcomes,” said Daniella Cramp, worldwide president of Cerenovus. “Cerenovus is committed to advancing treatment with evidence-based solutions so that fewer and fewer people are affected by the ravages of stroke.”

“The EmboTrap platform has been a great addition to my clinical practice. In my first nine cases using the device, I was able to get TICI 2b-3 reperfusion in one pass. Now, with the EmboTrap II, I’ve had comparably good results when treating longer occlusions,” said professor of radiology Christian Taschner, MD, of the University of Freiburg (Germany). “The open design of the device helps trap clot inside and also makes it quite flexible, which is important when removing clot from the arteries of the brain.”

Stent retrievers are deployed in an occluded vessel and are temporarily expanded into the body of a thrombus in order to recanalize the vessel, allowing for reperfusion of ischemic sites and causing the thrombus to be partially entangled within the stent. Thrombectomy is then performed by retracting the stent.

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