Drug Discovery Research Collaboration

Giles, UK) have announced a strategic alliance designed to employ sophisticated cellular genomics technologies and strategies to improve and accelerate the discovery and development of new drugs. This research collaboration will support the shared goals of translating basic genomic research into early health systems for some of the most pressing problems facing healthcare today.

TGen is focused on rapidly translating genomic developments into earlier diagnoses and more effective treatments that directly benefit patient care. "This collaboration could result in a better understanding of the biological mechanisms involved in oncology, many of which are not currently well understood by the medical community,” said Spyro Mousses Ph.D., director of Pharmaceutical Genomics and Cancer Drug Development at TGen. "The advanced imaging systems provided by GE allow us to observe cellular morphology more clearly and perform cytometry at an unprecedented rate. Most importantly, we can more accurately collect multi-parametric information about how cells are responding to specific genetic perturbations and to specific drug exposures.”

GE Healthcare's IN cell analyzer imaging systems are used by researchers in pharmaceutical and academic labs to assess a range of cellular processes in disease definition and drug development. TGen's high throughput cellular analysis research program will be equipped with both the IN cell analyzer 3000 and 1000. The new imaging systems will enable TGen investigators to functionally study the genome to identify and characterize cancer-associated genes that can be used to help develop more targeted medicines.

TGen is a non-profit organization focused on developing earlier diagnostics and better treatments. Translational genomics research is a somewhat new field employing innovative developments arising from the Human Genome Project and applying them to the development of diagnostics, prognostics, and therapies for cancer, neurological disorders, diabetes, and other complicated diseases.

GE Healthcare's expertise in medical imaging and information technologies, medical diagnostics, patient monitoring systems, drug discovery, and biopharmaceutical manufacturing technologies is helping clinicians worldwide provide new ways to predict, diagnose, inform and treat disease.



Related Links:
Translational Genomics Research Institute
GE Healthcare