We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Sekisui Diagnostics UK Ltd.

Download Mobile App




Game-Changing Endovascular Device-Based Approach Helps Patients Suffering From Heart Failure

By HospiMedica International staff writers
Posted on 24 Mar 2023
Print article
Image: The percutaneous EVBA procedure allows for precise placement of the MobiusHD implant in the target location (Photo courtesy of Vascular Dynamics)
Image: The percutaneous EVBA procedure allows for precise placement of the MobiusHD implant in the target location (Photo courtesy of Vascular Dynamics)

When there are changes in cardiac output, the baroreflex mechanism and baroreceptors react by stimulating the sympathetic system, leading to vasoconstriction and regulating heart rate and blood pressure to maintain homeostasis. However, in heart failure, the baroreflex becomes chronically impaired, causing excessive sympathetic activity and decreased parasympathetic activity, which ultimately overburdens the heart. For individuals with symptomatic heart failure who have already tried various medications without much improvement, a new percutaneous catheter-based therapy could potentially provide clinical relief.

The EVBA (endovascular baroreflex amplification) procedure using the unique MobiusHD device from Vascular Dynamics, Inc. (Irvine, CA, USA) stimulates the body's inherent mechanism to restore autonomic equilibrium and ease the heart's workload. The EVBA procedure involves the implantation of the MobiusHD device at a specific location within the carotid sinus. Prior to the procedure, imaging is conducted to pinpoint the optimal target site, and the entire process can be completed within 30 minutes on average.

By altering the shape of the carotid sinus to enhance local arterial wall stretch, the MobiusHD device induces mechanical stimulation of the arterial baroreceptor reflex. This, in turn, stimulates increased nerve signaling and triggers a reduction in sympathetic activity while augmenting parasympathetic activity, thereby rebalancing the autonomic nervous system. This modulation is believed to alleviate symptoms and slow the progression of HFrEF. As a result, the MobiusHD device may present a promising alternative solution for patients with symptomatic heart failure who have not responded well to traditional drug treatments.

A study evaluating the efficacy of the MobiusHD device in patients with progressive heart failure who remained symptomatic despite guideline-directed medical therapy recently presented two-year findings. The results revealed that the implantation of the device and its associated procedure led to continued enhancements in patient-centered outcomes, such as KCCQ scores, 6MWD, and NYHA class, alongside improvements in LVEF and NT-proBNP levels. These outcomes suggest that the EVBA procedure can offer a clinically meaningful and long-lasting benefit for certain heart failure patients.

Related Links:
Vascular Dynamics, Inc.

Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Gold Member
12-Channel ECG
CM1200B
Silver Member
Compact 14-Day Uninterrupted Holter ECG
NR-314P
New
Video Laryngoscope
SH-VL1

Print article

Channels

Surgical Techniques

view channel
Image: The multi-sensing device can be implanted into blood vessels to help physicians deliver timely treatment (Photo courtesy of IIT)

Miniaturized Implantable Multi-Sensors Device to Monitor Vessels Health

Researchers have embarked on a project to develop a multi-sensing device that can be implanted into blood vessels like peripheral veins or arteries to monitor a range of bodily parameters and overall health status.... Read more

Patient Care

view channel
Image: The portable, handheld BeamClean technology inactivates pathogens on commonly touched surfaces in seconds (Photo courtesy of Freestyle Partners)

First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds

Reducing healthcare-acquired infections (HAIs) remains a pressing issue within global healthcare systems. In the United States alone, 1.7 million patients contract HAIs annually, leading to approximately... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The Quantra Hemostasis System has received US FDA special 510(k) clearance for use with its Quantra QStat Cartridge (Photo courtesy of HemoSonics)

Critical Bleeding Management System to Help Hospitals Further Standardize Viscoelastic Testing

Surgical procedures are often accompanied by significant blood loss and the subsequent high likelihood of the need for allogeneic blood transfusions. These transfusions, while critical, are linked to various... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.