We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App

Lab-on-a-Patch Enables Continuous and Real-Time Monitoring of Multiple Disease Biomarkers

By HospiMedica International staff writers
Posted on 08 Jun 2023
Print article
Image: A breakthrough technology combines multiple DNA sensors with microneedles (Photo courtesy of Nutromics)
Image: A breakthrough technology combines multiple DNA sensors with microneedles (Photo courtesy of Nutromics)

Advancements in continuous glucose monitors (CGMs) have significantly improved the management of diabetes, however, they come with a major shortcoming: CGMs are incapable of measuring any diagnostic target other than glucose. Now, DNA-based sensing has emerged as a breakthrough technology that overcomes this limitation with its ability to enable continuous and real-time measurements of any diagnostic target.

Nutromics’ (Melbourne, Australia) is developing a "lab-in-a-patch" that harnesses DNA sensor technology to track various targets such as disease biomarkers and difficult-to-administer drugs within the human body. Currently undergoing in-human trial testing, Nutromics' DNA-based sensor platform is poised to bring about a significant shift in diagnostic methods. By integrating multiple DNA-based sensors with minimally invasive microneedles, the platform allows for continual and real-time tracking of various vital targets. With its aptamer platform, Nutromics stands to improve the prognosis for millions of patients in clinically critical conditions. By offering medical practitioners the ability to continuously monitor a wide array of analytes that presently cannot be analyzed in real-time, Nutromics’ "lab-in-a-patch could become a game changer in various clinical situations.

The initial product to come out from Nutromics’ stable is a wearable device equipped with a vancomycin sensor. Vancomycin, a potent antibiotic used for treating severe infections like sepsis, presents a dosage challenge due to its narrow therapeutic window, high toxicity, and limited patient blood level data available to doctors. DNA-based sensors can overcome these hurdles by providing continuous, real-time information on vancomycin concentration levels, enabling doctors to calibrate the antibiotic dosage to maintain the therapeutic range and avoid toxicity. Additionally, DNA-based sensors can significantly influence heart attack diagnosis. Troponin, a protein that markedly increases in the bloodstream upon heart muscle damage (like during a heart attack), can be continuously monitored to provide early trend data. This could drastically reduce heart attack diagnosis time to mere minutes, ultimately saving lives. Nutromics envisions a future where DNA-based biosensors extend beyond acute hospital settings to point-of-care, general lab testing, and even consumer use for the prevention of disease among healthy individuals.

Related Links:

Gold Member
STI Test
Vivalytic Sexually Transmitted Infection (STI) Array
Gold Member
POC Blood Gas Analyzer
Stat Profile Prime Plus
Silver Member
Compact 14-Day Uninterrupted Holter ECG
Drill Surgical Power Tool

Print article


Surgical Techniques

view channel
Image: ROSA Shoulder is a groundbreaking robotic system for anatomic and reverse shoulder arthroplasty (Photo courtesy of Zimmer Biomet)

World's First Robotic Assistant for Shoulder Replacement Surgery Helps Perform Highly Complex Procedures

A key challenge in performing a shoulder replacement is accurate glenoid and humeral placement, which is a critical factor for post-operative function and long-term implant survival. Now, a groundbreaking... Read more

Patient Care

view channel
Image: The newly-launched solution can transform operating room scheduling and boost utilization rates (Photo courtesy of Fujitsu)

Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization

An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The new eye-safe laser technology can diagnose traumatic brain injury (Photo courtesy of 123RF)

Novel Diagnostic Hand-Held Device Detects Known Biomarkers for Traumatic Brain Injury

The growing need for prompt and efficient diagnosis of traumatic brain injury (TBI), a major cause of mortality globally, has spurred the development of innovative diagnostic technologies.... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.