We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Sekisui Diagnostics UK Ltd.

Download Mobile App




Customizable Bio-Adhesive Patches for Different Organs Can Seal Internal Wounds

By HospiMedica International staff writers
Posted on 14 Feb 2024
Print article
Image: Researchers have developed novel underwater bio-adhesive patches with mussel adhesive protein (Photo courtesy of POSTECH)
Image: Researchers have developed novel underwater bio-adhesive patches with mussel adhesive protein (Photo courtesy of POSTECH)

The field of adhesives caters to a variety of applications, ranging from everyday uses in materials like paper and fabric to more specialized domains such as woodworking. In the medical field, adhesives are indispensable, serving purposes like suturing internal wounds and affixing sensors or medical devices. Now, researchers have achieved a breakthrough in this field by developing medical adhesives that can be tailored for different organs, offering not only superior underwater adhesion but also composed of natural materials to ensure safety and biocompatibility in the human body.

Researchers at POSTECH (Gyeongbuk. Korea) have developed customized underwater bio-adhesive patches (CUBAPs) by combining mussel adhesive protein with polyacrylic acid and polymethacrylic acid. In its dry form, the adhesive patch is non-sticky but becomes highly adhesive in the human body or other moist environments. The researchers have developed a way to modulate the degradation time and mechanical hardness by altering the ratios of polyacrylic acid and polymethacrylic acid. This adaptability allows for a personalized adhesive solution to meet the varied structural and biological requirements of different organs. The team has engineered three variants of these adhesive patches, successfully applying them in animal treatments and implants.

The CUBAPs demonstrated robust adhesion in highly dynamic organs, such as the heart and bladder. They also achieved positive outcomes in adjusting biodegradation periods and flexibility for the transplantation of muscle regeneration electronic devices. The CUBAPs can play a vital role in effectively sealing internal wounds, leaks, and perforations across various organs, thereby supporting healing and tissue regeneration. As the research and implementation of internal transplant devices grow, there is increasing demand for adhesives that can reliably secure these devices, ensuring robust underwater adhesion and minimal side effects. The customization of properties like biodegradation time is critical, given the distinct biological environments of different organs. Presently, the CUBAPs are under clinical assessment to reduce scarring in skin closures.

“This research paves the way for personalized medical applications. We plan to enhance and refine the process through subsequent studies, with the goal of effective applications in diverse biomedical fields,” said Hwa Hui Shin, a senior researcher from K-MEDI Hub. “Our study has confirmed the effectiveness and versatility of the developed bio-adhesive patches. We look forward to their evolving into commercial products, meeting the demands of the healthcare sector.”

Related Links:
POSTECH 

Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Gold Member
Disposable Protective Suit For Medical Use
Disposable Protective Suit For Medical Use
Silver Member
Wireless Mobile ECG Recorder
NR-1207-3/NR-1207-E
New
Computerized Spirometer
DatospirAira

Print article

Channels

Surgical Techniques

view channel
Image: The endoscopic device can 3D image the stiffness of individual biological cells and complex organisms (Photo courtesy of University of Nottingham)

World’s First Microscopic Probe to Revolutionize Early Cancer Diagnosis

In the early stages of cancer, the cells are significantly softer than normal cells, which facilitates their movement through small spaces and contributes to the rapid spread of the disease, a process... Read more

Patient Care

view channel
Image: The newly-launched solution can transform operating room scheduling and boost utilization rates (Photo courtesy of Fujitsu)

Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization

An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The Quantra Hemostasis System has received US FDA special 510(k) clearance for use with its Quantra QStat Cartridge (Photo courtesy of HemoSonics)

Critical Bleeding Management System to Help Hospitals Further Standardize Viscoelastic Testing

Surgical procedures are often accompanied by significant blood loss and the subsequent high likelihood of the need for allogeneic blood transfusions. These transfusions, while critical, are linked to various... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.