We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Sekisui Diagnostics UK Ltd.

Download Mobile App




Bioelectronic Mesh Grows With Cardiac Tissues for Comprehensive Heart Monitoring

By HospiMedica International staff writers
Posted on 22 Mar 2024
Print article
Image: The bioelectronic mesh can measure electrical signal and movement of cardiac tissue at the same time (Photo courtesy of UMass Amherst)
Image: The bioelectronic mesh can measure electrical signal and movement of cardiac tissue at the same time (Photo courtesy of UMass Amherst)

Heart disease remains the top cause of death worldwide. The ability to monitor heart tissue in real time is significantly limited. Implanting sensors in the heart is risky, and the heart's complexity—its mechanical actions of pumping blood and the electrical signals controlling those actions—demands monitoring of more than one characteristic at a time. However, traditional sensors can only track one feature, and a device capable of measuring both would be too large, potentially affecting the heart's function. Until now, no single sensor could assess both the heart's mechanical and electrical activities without affecting its operation. Now, researchers have created a bioelectronic mesh embedded with graphene sensors that can record the electrical signals and movements of cardiac tissue at the same time.

The tissue-like bioelectronic mesh system developed by a team of engineers led by the University of Massachusetts Amherst (Amherst, MA, USA) is integrated with an array of atom-thin graphene sensors and can simultaneously measure both the electrical signal and the physical movement of cells in lab-grown human cardiac tissue. This breakthrough allows for observation of the heart's development, providing insights into how its mechanical and electrical functions change over time. The device consists of two key components: a three-dimensional cardiac microtissue (CMT) derived from human stem cells that closely resembles a living human heart, and graphene, a one-atom-thick pure-carbon substance known for its electrical conductivity and piezoresistive properties. This means graphene can detect electrical activity and changes in resistance even when it is stretched, all without disrupting the heart's operations.

Embedded in a soft, stretchable, porous mesh scaffold that mimics human tissue, these graphene sensors can non-invasively attach to cardiac tissue, remaining stable and conductive over time. This allows for continuous monitoring of the CMT's development. This device is a significant advancement for cardiac disease research and the study of drug therapies' potential side effects. Going forward, the researchers aim to expand this technology for broader applications, including in vivo monitoring, to gather precise data to combat heart disease.

Related Links:
University of Massachusetts Amherst

Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Gold Member
12-Channel ECG
CM1200B
Silver Member
Wireless Mobile ECG Recorder
NR-1207-3/NR-1207-E
New
Oxidized Zirconium Implant Material
OXINIUM

Print article

Channels

Surgical Techniques

view channel
Image: The endoscopic device can 3D image the stiffness of individual biological cells and complex organisms (Photo courtesy of University of Nottingham)

World’s First Microscopic Probe to Revolutionize Early Cancer Diagnosis

In the early stages of cancer, the cells are significantly softer than normal cells, which facilitates their movement through small spaces and contributes to the rapid spread of the disease, a process... Read more

Patient Care

view channel
Image: The newly-launched solution can transform operating room scheduling and boost utilization rates (Photo courtesy of Fujitsu)

Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization

An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The Quantra Hemostasis System has received US FDA special 510(k) clearance for use with its Quantra QStat Cartridge (Photo courtesy of HemoSonics)

Critical Bleeding Management System to Help Hospitals Further Standardize Viscoelastic Testing

Surgical procedures are often accompanied by significant blood loss and the subsequent high likelihood of the need for allogeneic blood transfusions. These transfusions, while critical, are linked to various... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.