We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Sekisui Diagnostics UK Ltd.

Download Mobile App




Plasma Irradiation Promotes Faster Bone Healing

By HospiMedica International staff writers
Posted on 17 Apr 2024
Print article
Image: Effect of plasma irradiation on broken bone (Photo courtesy of Osaka Metropolitan University)
Image: Effect of plasma irradiation on broken bone (Photo courtesy of Osaka Metropolitan University)

While most bone fractures heal properly, about 5–10% do not, leading to delayed union or non-union conditions that can cause significant complications, persistent pain, and psychological distress, severely impacting the long-term quality of life. Particularly challenging are displaced or complex fractures that necessitate surgical intervention and extended periods of partial or full immobilization, complicating recovery and imposing significant economic burdens through indirect costs such as reduced productivity. Researchers are now exploring plasma irradiation as a novel method to accelerate bone healing and reduce recovery times.

The research group led by Osaka Metropolitan University (Osaka, Japan) conducted an experiment involving laboratory rats to test this approach. They induced two types of fractures in the rats: a group of 24 rats with normal fractures, typically quick to heal, and another group of 20 rats with non-union fractures, which are notoriously slow to heal or fail to heal altogether. The rats with non-union fractures were treated with non-thermal atmospheric-pressure plasma irradiation, which significantly enhanced their healing and recovery times, unlike in the normal fracture group where it showed no notable benefits.

Moreover, the healed bones in the plasma-treated non-union group were found to be approximately 3.5 times stronger than those in the non-treated group. Additionally, an in vitro study on pre-osteoblastic cells exposed to plasma for 5 to 15 seconds revealed increased activity of a protein indicative of osteoblast differentiation, suggesting progressive maturation of these bone-forming cells.

“In the future, combining this treatment method with current fracture treatments is expected to contribute to more reliable bone fusion and shorter recovery times,” said Hiromitsu Toyoda, Associate Professor at Osaka Metropolitan University.

Related Links:
Osaka Metropolitan University

Gold Member
STI Test
Vivalytic Sexually Transmitted Infection (STI) Array
Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Silver Member
Wireless Mobile ECG Recorder
NR-1207-3/NR-1207-E
New
Anesthesia Workstation
X40

Print article

Channels

Surgical Techniques

view channel
Image: The multi-sensing device can be implanted into blood vessels to help physicians deliver timely treatment (Photo courtesy of IIT)

Miniaturized Implantable Multi-Sensors Device to Monitor Vessels Health

Researchers have embarked on a project to develop a multi-sensing device that can be implanted into blood vessels like peripheral veins or arteries to monitor a range of bodily parameters and overall health status.... Read more

Patient Care

view channel
Image: The portable, handheld BeamClean technology inactivates pathogens on commonly touched surfaces in seconds (Photo courtesy of Freestyle Partners)

First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds

Reducing healthcare-acquired infections (HAIs) remains a pressing issue within global healthcare systems. In the United States alone, 1.7 million patients contract HAIs annually, leading to approximately... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The Quantra Hemostasis System has received US FDA special 510(k) clearance for use with its Quantra QStat Cartridge (Photo courtesy of HemoSonics)

Critical Bleeding Management System to Help Hospitals Further Standardize Viscoelastic Testing

Surgical procedures are often accompanied by significant blood loss and the subsequent high likelihood of the need for allogeneic blood transfusions. These transfusions, while critical, are linked to various... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.