Implantable Contour System Reshapes the Mitral Valve

The implant consists of a shaping ribbon between distal and proximal anchors, designed to be compatible with surrounding anatomy. The implant is delivered percutaneously via jugular vein access under fluoroscopic guidance, and is intended to be positioned and gently anchored in the coronary sinus or great cardiac vein. The surgeon then controls and adjusts the tension as needed, thus tightening the valve leaflets and improving mitral regurgitation. A recapture feature provides both a safety net and the ability to optimize result. The simple procedure takes less than one hour, and results are immediately observable; additionally, using the system does not preclude other HF therapies such as biventricular (Bi-V) pacing or surgery. Clinical tests have shown improvements in key parameters including New York Heart Association (NYHA) Classification, 6 Minute Walk distances, and Quality of Life (QOL). The Carillon Mitral Contour System is a product of Cardiac Dimensions (Kirkland, WA, USA), and has received the European Community (CE) marking of approval.

"In my experience with the device, the Carillon holds a great deal of promise for patients with functional mitral regurgitation. It has provided clinical benefit to those patients in whom I have placed it, and I see a tremendous opportunity for many more patients,” said Professor Michael Haude, M.D., of the Stadtische Kliniken Neuss (Germany).

Over 20 million people worldwide suffer from CHF. Most of these patients also suffer from dilated cardiomyopathy and FMR, the majority of whom are inadequately treated using medical management. While surgical options exist and can be effective in reducing FMR, they are infrequently used due to the burden of the surgery itself, which can be associated with high operative morbidity and mortality rates.

Related Links:
Cardiac Dimensions
Stadtische Kliniken Neuss