We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Bio-Expandable Bone Graft Could Help Spinal Surgery Patients

By HospiMedica International staff writers
Posted on 13 Apr 2016
Print article
Image: Expanding polymer bone graft to replace excised spinal tissue (Photo courtesy of Dr. Lichin Lu).
Image: Expanding polymer bone graft to replace excised spinal tissue (Photo courtesy of Dr. Lichin Lu).
An expandable, biodegradable graft could help metastatic spinal tumor patients recover from the surgical removal of bone segments and intervertebral discs, according to a new study.

Researchers at the Mayo Clinic (Rochester, MN, USA) have developed a biodegradable, hydrophilic, polymer graft that when surgically placed in the damaged vertebrae, expands to precisely fill the resected areas by absorbing bodily fluids. The graft is composed of two sections; a hollow hydrophilic scaffold made of crosslinked oligo(poly(ethylene glycol) fumarate) (OPF), and a stabilized polymer filler material. To develop the graft, the researchers first identified a combination of materials that are biocompatible in animals, and which they believe will work in humans.

To control the kinetics of the polymer graft expansion, the researchers made chemical changes to the filler to modify the degree and timing of the expansion, under conditions that mimicked the spinal column environment. The modulation of the molecular weight and charge of the polymer enabled them to tune the material’s properties so that the expansion rate was slow enough to enable surgeons to place it correctly, but fast enough so that it did not extend surgery times. The study was presented at the 251st national meeting & exposition of the American Chemical Society (ACS), held during March 2016 in San Diego (CA, USA).

“The overall goal of this research is to find ways to treat people with metastatic spinal tumors; the spine is the most common site of skeletal metastases in cancer patients, but unlike current treatments, our approach is less invasive and is inexpensive,” said lead author and study presenter Lichun Lu, PhD. “When we designed this expandable tube, we wanted to be able to control the size of the graft so it would fit into the exact space left behind after removing the tumor.”

Related Links:

Mayo Clinic

Print article


Patient Care

view channel
Image: The biomolecular film can be picked up with tweezers and placed onto a wound (Photo courtesy of TUM)

Biomolecular Wound Healing Film Adheres to Sensitive Tissue and Releases Active Ingredients

Conventional bandages may be very effective for treating smaller skin abrasions, but things get more difficult when it comes to soft-tissue injuries such as on the tongue or on sensitive surfaces like... Read more

Health IT

view channel
Image: AI can reveal a patient`s heart health (Photo courtesy of Mayo Clinic)

AI Trained for Specific Vocal Biomarkers Could Accurately Predict Coronary Artery Disease

Earlier studies have examined the use of voice analysis for identifying voice markers associated with coronary artery disease (CAD) and heart failure. Other research groups have explored the use of similar... Read more


view channel
Image: The global capsule endoscopy system market is growing at a rapid pace (Photo courtesy of Pexels)

Capsule Endoscopy System Market Driven by Rising Preference for Minimally Invasive Screening Procedure

Capsule endoscopy is generally a non-invasive technique that enables complete examination of the gastrointestinal tract with the use of the disposable and wireless device known as the video capsule.... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.