We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us
ARAB HEALTH - INFORMA

Download Mobile App




Fully Absorbable Stent Treats Coronary Artery Disease

By HospiMedica International staff writers
Posted on 18 Jul 2016
Print article
Image: The Absorb bioabsorbable drug-eluting stent (Photo courtesy of Abbott Vascular).
Image: The Absorb bioabsorbable drug-eluting stent (Photo courtesy of Abbott Vascular).
A new absorbable stent for treating coronary artery disease (CAD) releases everolimus to limit the growth of scar tissue.

The Absorb GT1 Bioresorbable Vascular Scaffold System (BVS) is made of a biodegradable poly-L-lactic acid (PLLA) and a poly-D,L-lactide (PDLLA) polymer coating that controls the release of the anti-proliferative drug everolimus. Once the vessel can remain open without the extra support, the stent is designed to slowly metabolize and eventually be resorbed by the body over a period of three years, leaving behind an intact vessel with the potential to flex, pulse, and dilate in response to various demands on the heart.

After absorption, there are only four small platinum markers left embedded in the walls of the artery, which help cardiologists identify where the Absorb GT1 BVS was originally placed. The dissolvable stent is delivered via the proprietary GlideTrack catheter, which is designed for optimal access in difficult anatomies. The Absorb GT1 BVS and GlideTrack catheter are products of Abbott Vascular (Santa Clara, CA, USA), and have been approved by the U.S. Food and Drug Administration (FDA).

“Abbott's goal is to help people everywhere live better, fuller and healthier lives,” said Deepak Nath, PhD, senior vice president of Abbott Vascular. “The Absorb bioresorbable stent treats coronary artery disease without committing people to a permanent metal implant, giving them peace of mind and helping them get back to their daily lives without the concern of having a permanent metallic implant.”

“This novel technology appeals to both physicians and patients alike, because after treating the underlying blockage it is completely absorbed, leaving nothing behind,” said Gregg Stone, MD, of Columbia University Medical Center (CUMC, New York, NY, USA). “No metal means the treated artery can pulse and flex naturally as demands on the heart change with everyday activities. No metal may also reduce the potential of future blockages that occur with permanent metallic stents, and allows easier access to other treatment options should they prove necessary in the patient's future.”

Everolimus is a derivative of sirolimus and functions as an inhibitor of mammalian target of rapamycin (mTOR). It is currently used as an immunosuppressant to prevent rejection of organ transplants and stents and as a treatment of renal cell cancer and other tumors.

Related Links:
Abbott Vascular


Gold Member
Real-Time Diagnostics Onscreen Viewer
GEMweb Live
Gold Member
12-Channel ECG
CM1200B
New
Diagnostic Ultrasound System
MS1700C
New
Blanket Warming Cabinet
EC250

Print article

Channels

Critical Care

view channel
Image: Changes in immune cells can predict patient recovery following out-of-hospital cardiac arrest (Photo courtesy of Adobe Stock)

Activating T Cells Could Improve Neurological Outcomes After Cardiac Arrest

Despite advancements in cardiopulmonary resuscitation (CPR) and improved hospital access, survival rates after out-of-hospital cardiac arrest (OHCA) remain low, with only about 10% of patients surviving.... Read more

Patient Care

view channel
Image: The portable biosensor platform uses printed electrochemical sensors for the rapid, selective detection of Staphylococcus aureus (Photo courtesy of AIMPLAS)

Portable Biosensor Platform to Reduce Hospital-Acquired Infections

Approximately 4 million patients in the European Union acquire healthcare-associated infections (HAIs) or nosocomial infections each year, with around 37,000 deaths directly resulting from these infections,... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The acoustic pipette uses sound waves to test for biomarkers in blood (Photo courtesy of Patrick Campbell/CU Boulder)

Handheld, Sound-Based Diagnostic System Delivers Bedside Blood Test Results in An Hour

Patients who go to a doctor for a blood test often have to contend with a needle and syringe, followed by a long wait—sometimes hours or even days—for lab results. Scientists have been working hard to... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.