We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Sekisui Diagnostics UK Ltd.

Download Mobile App

Endovascular Thrombectomy Improves Clinical Outcomes for Patients with Large Ischemic Stroke

By HospiMedica International staff writers
Posted on 21 Feb 2024
Print article
Image: Endovascular thrombectomy has been found to be beneficial for large ischemic stroke (Photo courtesy of 123RF)
Image: Endovascular thrombectomy has been found to be beneficial for large ischemic stroke (Photo courtesy of 123RF)

A new study has found that endovascular thrombectomy (EVT) can improve clinical outcomes for patients with acute ischemic stroke and large cores as compared with medical management.

Researchers from Case Western Reserve University (Cleveland, OH, USA) examined the relationship between imaging assessments of irreversible brain damage, areas at risk, and the clinical outcomes and effects of EVT treatment. This study spanning 31 international centers involved 336 patients who had acute ischemic stroke due to blockage of the internal carotid or the middle cerebral artery's M1 segment and a large ischemic core. Participants were randomly assigned to receive either EVT or medical management. The researchers found that EVT led to better functional outcomes compared to medical management.

This was particularly evident in an ordinal analysis of the modified Rankin Scale (mRS) at 90 days within certain categories of the Alberta Stroke Program Early Computed Tomography (CT) Score (ASPECTS) – specifically, categories 3, 4, and 5. The adjusted generalized odds ratios (aGenORs) for these categories were 1.71, 2.01, and 1.85, respectively. When comparing EVT with medical management, the aGenORs were 1.63, 1.41, and 1.47, respectively, for ischemic core volumes of ≥70, ≥100, and ≥150 mL, as measured by CT perfusion or magnetic resonance imaging (MRI). The study also found that outcomes in the EVT group tended to worsen as the ASPECTS decreased and as the CT perfusion/MRI ischemic volume increased, with aGenOR decreasing by 0.92 for every 10-mL increase in volume.

"EVT improved functional outcomes in ordinal analysis of the mRS score across a wide spectrum of ischemic injury extent when compared with medical management only," concluded the researchers.

Related Links:
Case Western Reserve University

Gold Member
POC Blood Gas Analyzer
Stat Profile Prime Plus
Gold Member
Real-Time Diagnostics Onscreen Viewer
GEMweb Live
Silver Member
Wireless Mobile ECG Recorder
Enterprise Imaging & Reporting Solution
Syngo Carbon

Print article


Patient Care

view channel
Image: The newly-launched solution can transform operating room scheduling and boost utilization rates (Photo courtesy of Fujitsu)

Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization

An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The Quantra Hemostasis System has received US FDA special 510(k) clearance for use with its Quantra QStat Cartridge (Photo courtesy of HemoSonics)

Critical Bleeding Management System to Help Hospitals Further Standardize Viscoelastic Testing

Surgical procedures are often accompanied by significant blood loss and the subsequent high likelihood of the need for allogeneic blood transfusions. These transfusions, while critical, are linked to various... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.