We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Comen Medical

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Bone Fiber Bullets Provide Improved Allograft Delivery

By HospiMedica International staff writers
Posted on 28 Jan 2021
Print article
Image: Lyophilized Fiber Bullets delivered through a cannula (Photo courtesy of TheraCell)
Image: Lyophilized Fiber Bullets delivered through a cannula (Photo courtesy of TheraCell)
A demineralized bone fiber (DBF) bullet facilitates grafting during minimally invasive surgery (MIS) orthopedic applications.

The TheraCell (Los Angeles, CA, USA) TheraFuze DBF Fiber Bullets are made from cortical DBF using a proprietary process that produces uniform six mm bullets, while still preserving the natural collagen structure. The Fiber Bullets can be inserted into a bone void or cage through a cannulated delivery system so that they can hydrate on site; as they hydrate, they form an entangled mass that resists migration and enhances the ability to fill defects completely, such as in endplate to endplate contact, which is important to achieving fusion.

The nanotopography of the DBF surface is designed to maintain the collagen structure of bone and to preserve its osteo-inductive proteins. This is achieved via patented processing technologies in which the mineral component of bone is removed prior to cleaving it along the axis of collagen orientation. The gentle process provides a nanotopographic structure unobtainable in conventional demineralized bone matrix products. The allograft also has an osteoinductive potential and enhanced handling properties that are ideal for spinal fusion and other orthopedic applications.

“I placed several Fiber Bullets in the lyophilized state anterior to the implant to fill the interbody space with graft material. Subsequent to the cage insertion, several additional Fiber Bullets were placed posterior to the cage to ensure complete endplate to endplate apposition,” said Neel Anand, MD, of Cedars Sinai Medical Center (Los Angeles, CA, USA), who used the bullets in an interbody TLIF cage procedure. “Delivery of the bullets through a cannula is a very convenient option. The entire procedure was quite simple and fit into my usual surgical process with ease.”

DBF is an autograft, allograft, or xenograft bone product prepared by removing inorganic minerals and leaving a matrix containing mainly collagen, and also allowing exposure of bone morphogenetic proteins (BMPs) that retain their biological activities.

Related Links:

Print article


Critical Care

view channel
Image: ID NOW (Photo courtesy of Abbott)

Abbott Displays Its Life-Changing POC Tests and Diagnostic Tools at MEDLAB Middle East

At the 2022 edition of MEDLAB Middle East, Abbott (Lake Forest, IL, USA) showcased its portfolio of life-changing diagnostic tools and medical devices for point-of-care testing that help manage patients... Read more


view channel

IBM Sells Watson Health Assets to Focus on Platform-Based Hybrid Cloud and AI Strategy

IBM (Armonk, NY, USA) and Francisco Partners (San Francisco, CA, USA) have signed a definitive agreement under which Francisco Partners will acquire healthcare data and analytics assets from IBM that are... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.