We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Detecto

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
16 Feb 2023 - 18 Feb 2023

Innovative Light-Triggered Coating for Medical Devices Fights Bacterial Infections

By HospiMedica International staff writers
Posted on 03 Nov 2022
Print article
Image: A durable coating for medical devices that is activated by light provides on-demand disinfection (Photo courtesy of Pexels)
Image: A durable coating for medical devices that is activated by light provides on-demand disinfection (Photo courtesy of Pexels)

Biofilms are the colonies of bacteria that grow on the surface of medical devices, such as catheters, implants, and wound meshes, and correlate with nosocomial infections. Bacterial biofilms on medical devices may result in infections and pose a serious threat to public health and economy, causing worldwide morbidity. Now, a team of researchers has developed a durable coating for medical devices which is activated by light, providing on-demand disinfection. The functional light-triggered coating for medical devices is very durable (stays there and retains its properties) and can destroy bacterial biofilms. The potential applications are for such coatings to be employed on medical devices that are often colonized by bacteria, such as catheters, endotracheal tubes, and wound dressings/meshes.

Light-triggered photocatalytic coatings destroy biofilms on-demand, but the challenge so far has been two-fold: first it is difficult to find materials that are activated by white light (and not harmful UV light) and second, to have them stable on medical devices and retain the activity over several cycles. Researchers at the Karolinska Institutet (Stockholm, Sweden) tackled both of these major challenges by producing materials that can be activated with white light and also inventing a new method to make these coatings highly durable, enabling them useful in repeated treatments.

The researchers produced the photocatalytic nanoparticle coating by a highly versatile nanomanufacturing technology, flame aerosol synthesis, and deposited them as porous films on the surface of the medical device. The researchers then went on to infuse the porous nanoparticle film with silicone (a polymer often used in medical devices) with a precise thickness, thereby dramatically increasing the durability of the produced coating. The researchers grew bacterial biofilms on the medical device - mimicking surfaces. The devices were then briefly irradiated for 15-90 minutes with white light which resulted in the on-demand biofilm destruction.

Biofilm infections tantalize several patients and the innovation here could mitigate this global health challenge by reducing such infections. Especially when such infections occur in immunocompromised patients, the clinical benefit is very high. The researchers have filed a patent application for their invention and are now further developing the product to assist in its rapid translation to clinics. Their next steps will be to develop this technology further as a coating on existing medical devices such as catheters, endotracheal tubes, and wound meshes/dressings, to name a few examples.

Related Links:
Karolinska Institutet

Gold Supplier
Disposable Protective Suit For Medical Use
Disposable Protective Suit For Medical Use
New
Blood Warmer
SAHARA-III 230 V
New
Ceiling-Mounted Digital X-Ray System
DigitalDiagnost C50
New
Orthopedic Table
GS GS-HV Series

Print article

Channels

AI

view channel
Image: A novel research study moves the needle on predicting coronary artery disease (Photo courtesy of Pexels)

AI-Enabled ECG Analysis Predicts Heart Attack Risk Nearly as well as CT Scans

Increased coronary artery calcium is a marker of coronary artery disease that can lead to a heart attack. Traditionally, CT scans are used to diagnose buildup of coronary artery calcium, although CT scanners... Read more

Critical Care

view channel
Image: The new biomaterial heals tissues from the inside out (Photo courtesy of UC San Diego)

Groundbreaking Biomaterial Injected Intravenously Repairs Cells and Tissue Damaged by Heart Attack and TBI

Following a heart attack, there is development of scar tissue, which affects muscle function and can result in congestive heart failure. However, there is still no established treatment available for repairing... Read more

Health IT

view channel
Image: Using digital data can improve health outcomes (Photo courtesy of Unsplash)

Electronic Health Records May Be Key to Improving Patient Care, Study Finds

When a patient gets transferred from a hospital to a nearby specialist or rehabilitation facility, it is often difficult for personnel at the new facility to access the patient’s electronic health records... Read more

Point of Care

view channel
Image: Steripath improves the diagnostic accuracy and timeliness of sepsis test results (Photo courtesy of Magnolia)

All-in-One Device Reduces False-Positive Diagnostic Test Results for Bloodstream Infections

Blood cultures are considered the gold standard diagnostic test for the detection of blood stream infections, such as sepsis. However, positive blood culture results can be frequently wrong, and about... Read more

Business

view channel
Image: The global patient positioning systems market is projected to reach USD 1.7 billion by 2027 (Photo courtesy of Pexels)

Global Patient Positioning Systems Market Driven by Increasing Chronic Diseases

The global patient positioning systems market is projected to grow at a CAGR of 4% from USD 1.4 billion in 2022 to USD 1.7 billion by 2027, driven by increasing technological advancements in medical devices,... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.