We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Radcal

Download Mobile App




First-in-Human Bladder Transplant to Revolutionize Treatment of Terminally Compromised Bladders

By HospiMedica International staff writers
Posted on 02 May 2023
Print article
Image: Urologists are set to perform the world’s first bladder transplant (Photo courtesy of USC Urology)
Image: Urologists are set to perform the world’s first bladder transplant (Photo courtesy of USC Urology)

Across the globe, hundreds of millions of people suffer from various degrees of bladder disease and dysfunction. Some of these patients may need a bladder reconstruction, a surgical procedure that involves removing the bladder and creating a new one from the patient's intestines. However, this surgery carries a high risk of early and delayed adverse side effects, and not every patient is eligible for the procedure. A team of urologists has now initiated a clinical trial to conduct the world's first human bladder transplant. The trial is actively screening potential participants for this groundbreaking transplantation. During the operation, the patient's diseased bladder will be removed and replaced with a healthy bladder from a deceased donor.

Bladder transplants have not been performed previously, partly due to the complex vascular structure of the pelvic area and the technical complexity of the procedure. For the past few years, surgeons at Keck Medicine of USC (Los Angeles, CA, USA) have been devising and practicing numerous research procedures in preparation for the first-of-its-kind bladder transplant, which will be conducted entirely using robotic surgery. This advanced form of minimally invasive surgery allows surgeons to employ a high-definition, three-dimensional camera to direct a robot in performing surgery through smaller, more accurate incisions with greater dexterity than possible with hand-held surgical instruments.

During the research and development phase, the surgeons successfully completed numerous practice transplantation surgeries, including the first-ever robotic bladder retrievals and successful robotic transplantations in five recently deceased donors whose cardiac function was maintained on ventilator support. The procurement, surgery, and post-surgical monitoring during transplantation adhered to current clinical and research standards.

“Transplantation is a lifesaving treatment option for conditions affecting many major organs, and transplanting a bladder could be a historic step in improving lives,” said Inderbir Gill, MD, founding executive director for USC Urology, part of Keck Medicine, who is also the principal investigator of the clinical trial and leading the transplantation efforts. “We could be on the verge of a medical advance that has the potential to revolutionize how we treat terminally compromised bladders.”

Related Links:
Keck Medicine of USC

Gold Member
Real-Time Diagnostics Onscreen Viewer
GEMweb Live
Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Silver Member
Compact 14-Day Uninterrupted Holter ECG
NR-314P
New
ECG Monitoring Solution
Bardy CAM Patch

Print article

Channels

Patient Care

view channel
Image: The portable, handheld BeamClean technology inactivates pathogens on commonly touched surfaces in seconds (Photo courtesy of Freestyle Partners)

First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds

Reducing healthcare-acquired infections (HAIs) remains a pressing issue within global healthcare systems. In the United States alone, 1.7 million patients contract HAIs annually, leading to approximately... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: POCT offers cost-effective, accessible, and immediate diagnostic solutions (Photo courtesy of Flinders University)

POCT for Infectious Diseases Delivers Laboratory Equivalent Pathology Results

On-site pathology tests for infectious diseases in rural and remote locations can achieve the same level of reliability and accuracy as those conducted in hospital laboratories, a recent study suggests.... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.