We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Feather Safety Razor

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Suture-Based Solution Corrects Structural Heart Defects

By HospiMedica International staff writers
Posted on 05 Dec 2017
Print article
Image: The Noblestitch EL percutaneous cardiovascular PFO closure system (Photo courtesy of HeartStitch).
Image: The Noblestitch EL percutaneous cardiovascular PFO closure system (Photo courtesy of HeartStitch).
An innovative percutaneous suturing system facilitates surgical repair of patent foramen ovale (PFO) and other heart defects.

The HeartStitch (Fountain Valley, CA, USA) Noblestitch EL is a percutaneous cardiovascular suturing and PFO closure system that allows surgeons to place a single polypropylene suture in order to close structural vascular defects. The system is composed of three devices for the release and attachment of non-absorbable polypropylene 4-0 sutures in three different steps:

The NobleStitch EL ‘S’ device allows the surgeon to place the first suture through the septum secundum;
The NobleStitch EL ‘P’ device allows the surgeon to place the second suture through the septum primum;
The “KwiKnot” device allows the surgeon to close the PFO by places a proprietary radiopaque polypropylene knot over the suture, eliminating the need to hand tie a knot.

Advantages of the system for treating PFO include no need for an implanted device, thus eliminating the subsequent risk of implant migration, dislocation, nickel allergy, late onset perforation, and erosion; no risk of thrombosis, and therefore no need for antiplatelet therapy or other medical treatment; and no interference with future transseptal procedures.

“Physicians continuously expressed to me their desire to have suture-based solutions rather than large metal implants left in the heart. Most physicians that have used the NobleStitch EL found it safe, easy to use, and have requested the same suture technologies to replace other implantable clips and devices,” said Professor Anthony Nobles, MD, inventor of the NobleStitch EL and Chairman, CEO and Chief Clinical Officer of HeartStitch. “With every new physician we proctor the response is universally one of 'I intend to use this in my patients as the first choice for closure. Eliminating the need for an anesthesiologist, we can perform the procedure safely under local anesthesia.”

“It is quite efficacious, and is possible to carry out in the majority of patients,” said Achille Gaspardone, MD, of San Eugenio Hospital (Rome, Italy), who presented data from several centers in Italy utilizing the NobleStitch EL system for PFO closure. “Most importantly, the system is safe because there is no metal device left behind, particularly on the left side of the heart.”

When the chambers of a human heart begin to develop, a tunnel is formed between the right and left atria of the heart in order to allow blood to flow directly from the venous to the arterial circulation, circumventing the non-functioning fetal lungs. Following birth, a pressure differential between the right and left atria forms to allow blood flow to the fully functioning lungs, and the tunnel eventually closes completely. When this does not occur, a PFO is formed, allowing blood clots and deoxygenated blood to o cross over to the arterial side. The presence of a PFO has been linked to a number of clinical issues, mainly strokes, migraines and chronic fatigue.

Related Links:

Print article


Critical Care

view channel
Image: Triage Cardiac Panel is a rapid, POC fluorescence immunoassay used with Triage MeterPro (Photo courtesy of Quidel)

Quidel Triage Cardiac Panel Facilitates Rapid POC Diagnosis of Chest Pain Patients in ED

Chest and abdominal pain are the most common reasons that persons aged 15 years and over visit the emergency department (ED). Because both emergency and non-emergency care are provided, symptoms vary widely... Read more

Patient Care

view channel
Image: Future wearable health tech could measure gases released from skin (Photo courtesy of Pexels)

Wearable Health Tech Could Measure Gases Released From Skin to Monitor Metabolic Diseases

Most research on measuring human biomarkers, which are measures of a body’s health, rely on electrical signals to sense the chemicals excreted in sweat. But sensors that rely on perspiration often require... Read more

Health IT

view channel
Image: AI can reveal a patient`s heart health (Photo courtesy of Mayo Clinic)

AI Trained for Specific Vocal Biomarkers Could Accurately Predict Coronary Artery Disease

Earlier studies have examined the use of voice analysis for identifying voice markers associated with coronary artery disease (CAD) and heart failure. Other research groups have explored the use of similar... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.