We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
GLOBETECH PUBLISHING LLC

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Digital Avatar Helps Plan Personalized Therapies

By HospiMedica International staff writers
Posted on 23 Jul 2019
Print article
Image: Research suggests virtual manikin avatars could help plan medical treatments (Photo courtesy of Empa).
Image: Research suggests virtual manikin avatars could help plan medical treatments (Photo courtesy of Empa).
A virtual doppelganger that is programmed with a patient’s physiological data could aid in providing a personalized prognosis of treatment.

Under development at the Swiss Federal Laboratories for Materials Science and Technology (Empa; Dübendorf, Switzerland), the digital twin represents a complex multi-physical skin model fed with data from non-invasive sensor systems attached to the human skin. The ostensible transdermal manikin and a linked-up computer model are then used to simulate human physiological responses to drugs and medicines, such as changes in skin temperature or perspiration rate, which can then be analyzed in order to enable precise and personalized dosage of the active agents.

The computer modeling of the digital doppelganger also factors in a patient’s skin characteristics. For example, the active agent will be absorbed differently depending on where the plaster is attached to the body, or whether the drug is administered to a sun-tanned athlete, an elderly lady with pale, papery skin, or a soft-skinned newborn. Drug dosage can thus be controlled precisely thanks to a tailored, time-dependent rate of expulsion. In the future, the manikins system will be used to set up the considerably more complex digital human doppelgangers, which are governed by a larger number of variables. The avatar was described on July 3, 2019, in CQFD.

“In medicine, people dream of complete in silico doppelgangers, which predict how a person will age or how an artificial joint will wear in the body. Using an in silico doppelganger, we’re able to respond to individual patients much more precisely,” said Professor Thijs Defraeye, PhD, of the Empa Biomimetic Membranes and Textiles lab. “As an extra benefit, we expect to be able to reduce the dosage (of painkillers, for instance) to such an extent that the patient is supplied with just the right amount.”

Related Links:
Swiss Federal Laboratories for Materials Science and Technology


Print article

Channels

AI

view channel
Image: Cardiologs Holter arrhythmia diagnostic software is cloud-based, vendor-neutral and powered by AI (Photo courtesy of Cardiologs)

AI Predicts Short-Term Risk of Atrial Fibrillation Using 24-Hour Holter Recordings

Atrial Fibrillation (AFib) affects millions of people each year. However, the condition is often unrecognized and untreated. Nowadays, patients are subject to 24-hour ambulatory electrocardiograms (ECGs)... Read more

Critical Care

view channel
Image: Cutting-edge 4D flow MRI scans could revolutionize blood flow assessment in the heart (Photo courtesy of University of East Anglia)

4D Flow MRI Scans Could Revolutionize Diagnosis of Patients with Heart Failure

Researchers have developed cutting-edge imaging technology to help doctors better diagnose and monitor patients with heart failure. The state-of-the-art technology uses magnetic resonance imaging (MRI)... Read more

Surgical Techniques

view channel
Image: The Senhance surgical system with digital laparoscopy (Photo courtesy of Asensus Surgical)

Digital Laparoscopic Platform Leverages Augmented Intelligence and Machine Learning

Challenges in laparoscopic surgery can impact cost, utilization, effectiveness, and outcomes of the procedure. For instance, the inability of the surgeon to control vision can create efficiency and safety... Read more

Patient Care

view channel
Image: The biomolecular film can be picked up with tweezers and placed onto a wound (Photo courtesy of TUM)

Biomolecular Wound Healing Film Adheres to Sensitive Tissue and Releases Active Ingredients

Conventional bandages may be very effective for treating smaller skin abrasions, but things get more difficult when it comes to soft-tissue injuries such as on the tongue or on sensitive surfaces like... Read more

Business

view channel
Image: Expanding the role of autonomous robots can mitigate the shortage of physicians (Photo courtesy of Pexels)

Robot-Assisted Surgical Devices Market Driven by Increased Demand for Patient-Specific Surgeries

An aging population and accompanying retirements will cause a significant physician shortfall of 55,000 to 150,000 by 2030, creating a gap in the healthcare system. Expanding the role of autonomous robots... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.