We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Detecto

Varian Medical Systems

Provides solutions for advancing cancer treatment, radiosurgery, X-ray imaging, & security, radiotherapy, radiosurger... read more Featured Products: More products

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
16 Feb 2023 - 18 Feb 2023

Microsphere Embolization Technology Treats Knee Osteoarthritis

By HospiMedica International staff writers
Posted on 26 Oct 2021
Print article
Image: Embozene microspheres are color-coded by size (Photo courtesy of Varian)
Image: Embozene microspheres are color-coded by size (Photo courtesy of Varian)
Novel microspheres can alleviate symptomatic knee osteoarthritis (OA) by reducing blood flow to the periarticular tissue of the joints, limiting the inflammatory process.

The Varian Medical Systems (Varian; Palo Alto, CA, USA) Embozene spheres are biocompatible hydrogel microspheres coated with a proprietary polymer (Polyzene-F). The minute spheres are color-coded by size to allow for easy identification, and are delivered pre-compressed to enable smooth delivery via catheter. Embozene microspheres are intended for embolization of arteriovenous malformations and hypervascular tumors, such as uterine fibroids and hepatoma, benign prostatic hyperplasia (BPH), and now for genicular artery embolization (GAE).

GAE is performed under moderate sedation as an outpatient procedure, generally taking one to two hours. The delivery catheter is inserted in a percutaneous procedure under fluoroscopic guidance, with the microspheres conveyed to arteries supplying the inflamed synovium (lining of the knee). By blocking the genicular arteries, there is a reduction in the amount of inflammation associated with OA, which can diminish or eliminate the associated knee pain. Embozene microspheres are packaged in 20 ml syringes, with an approximate 7 ml fill volume across the range.

“GAE holds great promise in providing clinicians with a new, non-invasive treatment option, which may not only ameliorate pain, but reduce the economic burden of this common disease,” said Frank Facchini, MD, president of Varian Interventional Solutions. “Varian's investigational program for GAE exemplifies our commitment to investing in our core technologies to determine their potential to treat the world's most debilitating diseases.”

“GAE is the first minimally invasive procedure that has demonstrated significant symptom improvement for a prolonged duration,” said Siddharth Padia, MD, director of interventional radiology at UCLA Santa Monica (CA, USA). “In a 40-patient, prospective study, the procedure resulted in a marked improvement in pain and function, and adverse events were uncommon and mild. I remain excited about the possibilities of this technology and its benefit to patients.”

OA is a group of abnormalities involving degradation of joints, including articular cartilage and subchondral bone. Symptoms may include joint pain, tenderness, stiffness, locking, and sometimes an effusion. A variety of causes--hereditary, developmental, metabolic, and mechanical deficits--may initiate processes leading to loss of cartilage. As a result of decreased movement secondary to pain, regional muscles may atrophy, and ligaments may become more lax. OA of the knee affects about 250 million people worldwide (3.6% of the population).

Related Links:
Varian Medical Systems

Gold Supplier
Temperature Monitor
ThermoScan Temperature Monitoring Unit
New
Ceiling-Mounted Digital X-Ray System
DigitalDiagnost C50
New
Mechanical Ventilator
NKV-550 Series
New
Capnograph/Pulse Oximeter
Handleld Capnograph/Pulse Oximeter

Print article

Channels

AI

view channel
Image: A novel research study moves the needle on predicting coronary artery disease (Photo courtesy of Pexels)

AI-Enabled ECG Analysis Predicts Heart Attack Risk Nearly as well as CT Scans

Increased coronary artery calcium is a marker of coronary artery disease that can lead to a heart attack. Traditionally, CT scans are used to diagnose buildup of coronary artery calcium, although CT scanners... Read more

Critical Care

view channel
Image: The advanced electronic skin could enable multiplex healthcare monitoring (Photo courtesy of Terasaki Institute)

First-of-Its-Kind Electronic Skin Patch Enables Advanced Health Care Monitoring

For some time now, electronic skin (E-skin) patches have been used to monitor bodily physiological and chemical indicators of health. Such monitors, placed on the skin, are capable of measuring various... Read more

Surgical Techniques

view channel
Image: The neuro-chip with soft implantable electrodes could manage brain disorders (Photo courtesy of EPFL)

Implantable Neuro-Chip Uses Machine Learning Algorithm to Detect and Treat Neurological Disorders

Using a combination of low-power chip design, machine learning algorithms, and soft implantable electrodes, researchers have produced a neural interface that can identify and suppress symptoms of different... Read more

Health IT

view channel
Image: Using digital data can improve health outcomes (Photo courtesy of Unsplash)

Electronic Health Records May Be Key to Improving Patient Care, Study Finds

When a patient gets transferred from a hospital to a nearby specialist or rehabilitation facility, it is often difficult for personnel at the new facility to access the patient’s electronic health records... Read more

Point of Care

view channel
Image: Steripath improves the diagnostic accuracy and timeliness of sepsis test results (Photo courtesy of Magnolia)

All-in-One Device Reduces False-Positive Diagnostic Test Results for Bloodstream Infections

Blood cultures are considered the gold standard diagnostic test for the detection of blood stream infections, such as sepsis. However, positive blood culture results can be frequently wrong, and about... Read more

Business

view channel
Image: Researchers expect broader adoption of AI in healthcare in the near future (Photo courtesy of Pexels)

Artificial Intelligence (AI) Could Save U.S. Healthcare Industry USD 360 Billion Annually

The wider adoption of artificial intelligence (AI) in healthcare could save the U.S. up to USD 360 billion annually although its uptake in the industry is presently limited owing to the absence of trust... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.