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GSK and Sanofi to Supply UK with 60 Million Doses of Recombinant Protein-Based COVID-19 Vaccine

By HospiMedica International staff writers
Posted on 30 Jul 2020
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GlaxoSmithKline plc (London, UK) and Sanofi S.A. (Paris, France) have entered into an agreement with the UK government for the supply of up to 60 million doses of a COVID-19 vaccine.

The vaccine candidate, developed by Sanofi in partnership with GSK, is based on the recombinant protein-based technology used by Sanofi to produce an influenza vaccine, and GSK’s established pandemic adjuvant technology. Sanofi is leading the clinical development and registration of the COVID-19 vaccine and expects a Phase 1/2 study to start in September, followed by a Phase 3 study by the end of 2020. If the data are positive, regulatory approval could be achieved by the first half of 2021. In parallel, Sanofi and GSK are scaling up manufacturing of the antigen and adjuvant to produce up to one billion doses per year overall.

Sanofi and GSK are committed to making the vaccine available globally and are holding active discussions on supply of the vaccine with global organizations. The companies plan to provide a significant portion of total worldwide available supply capacity in 2021/22 to the global initiative, “Access to COVID‐19 Tools (ACT) Accelerator”, a global collaboration of leaders of governments, global health organizations, businesses and philanthropies to accelerate development, production, and equitable access to COVID-19 tests, treatments, and vaccines.

“With our partner GSK, we are pleased to cooperate with the UK government as well as several other countries and global organizations as part of our ongoing efforts to develop a safe and effective vaccine and make it available as quickly as possible. We greatly appreciate the UK government’s support of this shared vision,” said Thomas Triomphe, Executive Vice President and Global Head of Sanofi Pasteur.

“We believe that this adjuvanted vaccine candidate has the potential to play a significant role in overcoming the COVID-19 pandemic, both in the UK and around the world. We thank the UK government for confirmation of purchasing intent, which supports the significant investment we are already making as a company to scale up development and production of this vaccine,” added Roger Connor, President of GSK Vaccines.

“Through this agreement with GSK and Sanofi, the Vaccine Taskforce can add another type of vaccine to the three different types of vaccine we have already secured,” said Kate Bingham, Chair of the UK Government’s Vaccines Taskforce. “This diversity of vaccine types is important because we do not yet know which, if any, of the different types of vaccine will prove to generate a safe and protective response to COVID-19. Whilst this agreement is very good news, we mustn’t be complacent or over optimistic. The fact remains we may never get a vaccine and if we do get one, we have to be prepared that it may not be a vaccine which prevents getting the virus, but rather one that reduces symptoms.”

Related Links:
GlaxoSmithKline plc
Sanofi S.A.



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