We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Sekisui Diagnostics UK Ltd.

Download Mobile App





Chest CT Scans of COVID-19 Patients Could Help Distinguish Between SARS-CoV-2 Variants

By HospiMedica International staff writers
Posted on 28 Jun 2022
Print article
Image: Chest CTs reveal Omicron variant is less severe than Delta variant infection (Photo courtesy of Oxford University)
Image: Chest CTs reveal Omicron variant is less severe than Delta variant infection (Photo courtesy of Oxford University)

The SARS-CoV-2 Omicron variant has demonstrated rapid spread but with reduced disease severity. Patients with Omicron infection have half the odds of hospitalization and of severe disease than those infected with Delta and preceding variants. Furthermore, the risk of being admitted to hospital for Omicron infection is 65% lower for vaccinated compared to unvaccinated individuals. However, there is limited data on differential severity and outcomes between variants once patients are admitted to hospital for SARS-COV-2. A recent study had demonstrated that vaccinated patients with SARS-COV-2 ‘breakthrough’ infections show fewer chest CT findings of pneumonia compared with unvaccinated patients, although variant status in this study was unknown. Now, a new study has found that the SARS-COV-2 Omicron variant is associated with fewer and less severe changes on chest CT compared with the Delta variant. The study also found that patients with Omicron had greater frequency of bronchial wall thickening but lower clinical severity and improved hospital outcomes than those with Delta.

In a retrospective analysis, researchers at the Oxford University Hospitals NHS Foundation Trust (Oxford, UK) compared the radiological pattern, imaging characteristics and disease severity on initial CT pulmonary angiograms of patients infected with the Omicron variant with those infected with the Delta variant, as well as compared the imaging severity according to vaccination status.

In a small series of hospitalized patients who had tested RT-PCR positive for SARS-CoV-2 with CT pulmonary angiography performed within seven days of admission, the researchers found that the Omicron variant infection is less likely to be associated with SARS-CoV-2 pneumonia, and that, when pneumonia does occur, it is less severe on chest CT. In agreement with chest CT patterns, Omicron infection was associated with reduced clinical and biochemical markers of severity and improved hospital outcomes. The researchers found lower CT severity scores (7.2) and increased incidence of bronchial wall thickening in the Omicron group. In terms of vaccination status, those who were vaccinated also recorded lower CT severity scores. These findings were consistent, regardless of the interpreting radiologist’s experience level.

Related Links:
Oxford University Hospitals NHS Foundation Trust


Print article

Channels

Surgical Techniques

view channel
Image: The PtNGrid features thin, flexible and densely packed grids of either 1,024 or 2,048 embedded ECoG sensors (Photo courtesy of David Baillot/UC San Diego Jacobs School of Engineering)

Electronic Grid Records Brain Activity during Surgery to Minimize Damage to Healthy Tissue

A new electronic grid equipped with nanoscale sensors that records electrical signals from the human brain with unprecedented detail could enhance surgical planning and execution for removing brain tumors... Read more

Patient Care

view channel
Image: The portable, handheld BeamClean technology inactivates pathogens on commonly touched surfaces in seconds (Photo courtesy of Freestyle Partners)

First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds

Reducing healthcare-acquired infections (HAIs) remains a pressing issue within global healthcare systems. In the United States alone, 1.7 million patients contract HAIs annually, leading to approximately... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: POCT offers cost-effective, accessible, and immediate diagnostic solutions (Photo courtesy of Flinders University)

POCT for Infectious Diseases Delivers Laboratory Equivalent Pathology Results

On-site pathology tests for infectious diseases in rural and remote locations can achieve the same level of reliability and accuracy as those conducted in hospital laboratories, a recent study suggests.... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.