We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Minimally Invasive Technique Demonstrates Positive Surgical Outcome in Treatment of Hemorrhagic Strokes

By HospiMedica International staff writers
Posted on 27 Apr 2023
Print article
Image: The BrainPath family of products includes 13.5mm and 11mm diameter devices of various lengths (Photo courtesy of NICO)
Image: The BrainPath family of products includes 13.5mm and 11mm diameter devices of various lengths (Photo courtesy of NICO)

Annually, hemorrhagic strokes affect two million people, representing the most lethal, expensive, and debilitating type of stroke. This kind of stroke occurs when a weakened blood vessel ruptures and bleeds into the brain, causing toxic blood to accumulate. Regrettably, nearly 50% of hemorrhagic stroke victims die within a month. Studies indicate that removing blood from the brain within 24 hours of the bleeding onset could minimize brain damage and fatalities. Currently, the standard treatment involves administering medication or adopting a "watch and see" approach, potentially prolonging blood presence in the brain and raising the risk of complications. Researchers have now announced promising results from a surgical treatment trial for hemorrhagic strokes, showing positive outcomes in treating intracerebral hemorrhage (ICH).

In the ENRICH (Early MiNimally-invasive Removal of ICH) randomized, multi-center clinical trial led by Emory University School of Medicine (Atlanta, GA, USA), researchers compared standard medical management to early minimally invasive parafascicular surgery (MIPS) using the BrainPath and Myriad technology from NICO Corporation (Indianapolis, IN, USA). The BrainPath device assists surgeons in reaching the bleeding site in the brain by delicately navigating through its folds and fibers, gently displacing brain tissue to create a pathway. Once at the site, the Myriad device, an automated suction and resection tool, removes the clot.

After six months, functional outcomes in ENRICH were assessed using the utility-weighted modified Rankin Scale (UWmRS), with scores above zero indicating improved results. The mean UWmRS score was 0.458 for the MIPS group and 0.374 for those receiving standard medical management, reflecting a 98.1% posterior probability of superiority. This difference fulfilled the primary endpoint, proving a statistically significant and clinically meaningful improvement in UWmRS for the MIPS group. The ENRICH study also determined MIPS to be safe, with an overall mortality rate of 21.7% at six months (20% for MIPS, 23.3% for the standard medical management group). In the MIPS group, median hematoma evacuation was 88%, with a median end-of-treatment volume (EOTV) of 7.2mL. Overall, 73% of patients achieved the EOTV goal of less than 15mL, considered the surgical standard in clot evacuation.

“The results of the ENRICH trial are revolutionary and represent an advancement for improving outcomes for the millions of people who suffer hemorrhagic strokes,” said Jim Pearson, president and CEO, NICO Corporation.

“ENRICH is the first, randomized clinical trial to meet its primary endpoint, while improving outcomes for these deadly strokes,” said Gustavo Pradilla, MD, co-lead investigator for ENRICH, associate professor of neurosurgery at Emory University School of Medicine and chief of neurosurgery for Grady Memorial Hospital. “This trial will help to change how we treat hemorrhagic stroke moving forward.”

Related Links:
Emory University School of Medicine 
NICO Corporation 

Gold Supplier
Ultrasound Phantom
Multi-Purpose Multi-Tissue Ultrasound Phantom - Model 040GSE
Multi-Parameter Patient Monitor
CFM Device
EEGDigiTrack CFM/aEEG Devices
Endoscopic Irrigation Pump

Print article
FIME - Informa



view channel
Image: The AI tool can also tackle dangerous inequalities in heart attack diagnosis (Photo courtesy of Freepik)

AI Algorithm Integrates Cardiac Troponin Test Results with Clinical Data to Quickly Rule out Heart Attacks in Patients

The accepted standard for diagnosing myocardial infarction, or heart attack, involves assessing the blood for troponin levels. However, this approach applies the same benchmark for all patients, failing... Read more

Surgical Techniques

view channel
Image: The deployable electrodes are ideal for minimally invasive craniosurgery (Photo courtesy of EPFL)

Soft Robotic Electrode Offers Minimally Invasive Solution for Craniosurgery

Minimally invasive medical procedures offer numerous benefits to patients, including decreased tissue damage and shorter recovery periods. However, creating equipment that can pass through a small opening... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: IntelliSep is the first FDA-cleared diagnostic tool to assess cellular host response to aid in identifying ED patients with sepsis (Photo courtesy of Cytovale)

Rapid Microfluidic Test Demonstrates Efficacy as Diagnostic Aid to Improve Sepsis Triage in ED

Sepsis is the primary cause of mortality worldwide, accounting for over 350,000 fatalities annually in the United States alone, a figure that surpasses deaths from opioid overdoses, prostate cancer, and... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.