We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App




Mobile Phone Microscope Aids Malaria Diagnosis

By HospiMedica International staff writers
Posted on 16 Sep 2015
Print article
Image: The MOPID device atached to an iPhone (Photo courtesy Casey of Pirnstill/ TAMU).
Image: The MOPID device atached to an iPhone (Photo courtesy Casey of Pirnstill/ TAMU).
A 3-D printed polarized microscope that can be attached to a mobile phone could help faster malaria detection in areas with limited access to expensive lab facilities and expert technicians.

Developed by researchers at Texas A&M University (TAMU; College Station, TX, USA), the low-cost, lightweight, high quality mobile-optical-polarization imaging device (MOPID) offers 40–100x magnification, sufficient to image pigmentation of the hemozoin crystal, a waste product produced by ‎Plasmodium falciparum, the parasite that causes malaria. To perform the test, a glass slide with a blood smear is inserted into the device; the cell phone camera then takes a picture, and the photo shows the presence (or absence) of malaria.

The MOPID system consists of a commercial Apple iPhone 5S cellular phone, a snap on 3D-printed cartridge with individual compartments that allowed for polarized microscopy, two polarizer sheets, low-power white light emitting diodes (LEDs), and a plastic lens assembly configuration allowing for appropriate magnification, resolution, and field of view (FOV) for diagnosing the presence of the malaria parasite. The analyzer can be rotated to vary the degree of polarization, thus allowing for birefringence measurements from the hemozoin crystal.

The researchers are moving forward to construct a more durable, compact, and cheaper device for in vivo field-testing in Rwanda. They envision that the final product could be available for less than USD 1.00 per test result, not including the cost of the mobile phone attached to the MOPID device. A study describing the system and comparing performance to a Leica Microsystems (Wetzlar, Germany) DMLM polarized white light microscope was published on August 25, 2015, in Nature Scientific Reports.

“Because of the lack of access to lab testing, many health-care providers rely on rapid diagnostic tests, which are the equivalent of a pregnancy test for parasites. They are not always reliable and can lead to misdiagnosis and overtreatment. Giving medicine to those who don’t need it is causing drug-resistant strains of malaria to develop,” said lead author biomedical engineer Casey Pirnstill, BSc. “The device could be used by a nurse or other health outreach workers. The original photos would be saved in case further interpretation by a doctor is required.”

There are more than 200 million new malaria cases yearly, and high-quality microscopy is still the most accurate method for detection of infection. Microscopy, however, requires well-trained personnel and can be very time-consuming. As a result, less than half of the suspected malaria cases in Sub-Saharan Africa in 2012 received a diagnostic test.

Related Links:

Texas A&M University
Leica Microsystems


Gold Member
Solid State Kv/Dose Multi-Sensor
AGMS-DM+
Gold Member
POC Blood Gas Analyzer
Stat Profile Prime Plus
Silver Member
Compact 14-Day Uninterrupted Holter ECG
NR-314P
New
Brachytherapy Planning System
Oncentra Brachy

Print article

Channels

Critical Care

view channel
Image: Detecting heart diseases using AI and the ECG (Photo courtesy of 123RF)

AI Technology Boosts ECG Capabilities for Early Heart Disease Diagnosis

Cardiovascular diseases often remain undetected until a critical event like a heart attack or stroke occurs. Early identification is key to improving outcomes, but the absence of clear symptoms complicates... Read more

Surgical Techniques

view channel
Image: Real-time navigation is a useful tool for ablation procedures to destroy tumors in the liver (Photo courtesy of University of Cincinnati)

Real-Time Navigation Found To Be Useful Tool for Liver Cancer Procedures

Liver cancer, ranking as the world's fourth most common cause of cancer-related deaths, presents a significant health challenge. For certain patients, ablation offers a less invasive alternative to traditional... Read more

Patient Care

view channel
Image: The newly-launched solution can transform operating room scheduling and boost utilization rates (Photo courtesy of Fujitsu)

Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization

An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more

Point of Care

view channel
Image: The new eye-safe laser technology can diagnose traumatic brain injury (Photo courtesy of 123RF)

Novel Diagnostic Hand-Held Device Detects Known Biomarkers for Traumatic Brain Injury

The growing need for prompt and efficient diagnosis of traumatic brain injury (TBI), a major cause of mortality globally, has spurred the development of innovative diagnostic technologies.... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.