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Image: A novel anti-inflammatory peptide could prevent cytokine storm in COVID-19 patients (Photo courtesy of University of Toronto)

Organ-on-a-Chip Platform Helps Devise Strategy to Treat Severe COVID-19 Complications

One of the greatest challenges for clinicians during the COVID-19 pandemic has been to understand why some people infected by the SARS-CoV-2 virus experience cytokine storms, while others do not. Using their novel organ-on-a-chip platform, researchers have now identified a molecule with the potential to combat cytokine storms, one of the most severe complications of COVID-19 infections. More...
30 Mar 2022
Image: 10-minute IntelliSep Sepsis Test (Photo courtesy of Cytovale)

10-Minute Sepsis Risk Test Demonstrates Potential to Rapidly Risk-Stratify Suspected COVID-19 Patients

A novel test designed to quantify the state of immune activation by measuring the biophysical properties of leukocytes from a routine blood sample in less than 10 minutes has the potential to rapidly risk-stratify patients independent of pathogen, according to a new study. This finding is important as risk stratification may improve resource allocation in hospitals. More...
23 Mar 2022
Image: Ground-breaking technologies will assess organ and tissue damage in transplant and COVID-19 patients (Photo courtesy of Pexels)

Ground-Breaking and Novel Assays to Help Assess Organ and Tissue Damage in Transplant and COVID-19 Patients

A new collaboration will expand access to blood and urine-based cell-free DNA detection methods that will provide healthcare practitioners with highly accurate, non-invasive tools to identify and monitor for infection, rejection, and severity of organ damage in transplant and COVID-19 patients. More...
22 Mar 2022
Image: Urine proteome contains clues to what is happening inside the human body (Photo courtesy of Unsplash)

Urinary Proteome Analysis Predicts Transition from Moderate to Severe Disease in COVID-19 Progression

Since the pandemic broke out, a team of researchers working in the forefront line of compacting COVID-19 disease have been investigating whether they could find clues for what happened to the living COVID-19 patients at the molecular level. As urine can be readily obtained from living people, they looked at all kinds of proteins in the urine. Their latest findings suggest that urine may provide a window for us to see what is happening inside the human body and predict the transition from moderate to severe disease in COVID-19 progression. More...
21 Mar 2022
Image: Researchers detected air trapping on expiratory chest CT images of post-COVID patients (Photo courtesy of Pexels)

AI-Based Analysis of Expiratory Chest CT Images of Post-COVID Patients Shows Evidence of Small Airways Disease

Early reports indicate that more than 50% of adult survivors of SARS-CoV-2 infection experience post-acute sequelae of COVID-19 (PASC), more commonly known as “long COVID.” Respiratory symptoms, including cough and dyspnea, are reported by nearly 30% of patients with long COVID, including those who experienced mild infection. Now, a new study has found air trapping, indicative of small airways disease, in patients with lingering respiratory symptoms after COVID-19 infection. More...
18 Mar 2022
Image: Digital images of cells infected with SARS-CoV-2 created from soft X-ray tomography (Photo courtesy of Berkeley Lab)

Soft X-Ray Tomography 3D Scans Show How Cells Respond to SARS-CoV-2 Infection and to Possible Treatments

An extremely fast new 3D imaging method can show how cells respond to SARS-CoV-2 infection and to possible treatments. More...
28 Feb 2022
Illustration

Study Proposes New Guidelines to Design Mechanical Ventilators That Can Work in Low- and Middle-Income Countries

A study has proposed essential new guidelines to design mechanical ventilators that can work in low- and middle-income countries (LMICs). More...
10 Feb 2022
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