We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App




Early Onset Colorectal Cancer Rising in High-Income Countries

By HospiMedica International staff writers
Posted on 17 Sep 2019
Print article
A new study finds that colorectal cancer (CRC) incidence is increasing exclusively in young adults residing in high-income countries spanning three continents.

Researchers at the American Cancer Society (Atlanta, GA, USA), the International Agency for Research on Cancer (Lyon, France), and the Northwell Health Cancer Institute (Great Neck; NY, USA) extracted long-term data on cancer incidence in order to examine CRC incidence rates and trends (by age) through diagnosis of data from 2012 (or beyond) in five continents. For comparison, during 2008–2012, age-standardized CRC incidence rates in adults younger than 50 ranged from 3.5 per 100,000 in India to 12.9 in Korea, and were stable in 14 of 36 countries.

The results revealed that of the 36 countries with sufficient numbers of cases to analyze trends, CRC incidence rates decreased in three (Italy, Austria, and Lithuania), and increased in 19. In nine of those 19 countries, the rise in early-onset CRC was in contrast to trends in patients 50 years of age and older, which were either dropping (Australia, New Zealand, Canada, Germany, and United States) or stable (Denmark, Slovenia, Sweden, and United Kingdom). The steepest increases in young adults were in Korea and New Zealand. The study was published on September 5, 2019, in the journal Gut.

“These patterns potentially signal changes in early-age exposures conducive to large bowel carcinogenesis, and highlight an urgent need for research to explore the potentially unique etiology of young-onset CRC,” said lead author Rebecca Siegel, MPH, of American Cancer Society. “Although the absolute risk of CRC in adults younger than 50 years is low relative to older adults, disease trends in young age groups are a key indicator of recent changes in risk factor exposures and often foreshadow the future cancer burden.”

Declining cancer incidence in older adults in many countries is partly attributed to CRC screening, which typically emerged over the past two decades and begins between the ages of 50 and 60 years. However, Austria and Italy, two of only three countries where early-onset CRC incidence is declining, have been screening adults beginning at age 40 and 45 years, respectively, since the early 1980s.

Related Links:
American Cancer Society
International Agency for Research on Cancer
Northwell Health Cancer Institute

Gold Member
Real-Time Diagnostics Onscreen Viewer
GEMweb Live
Gold Member
STI Test
Vivalytic Sexually Transmitted Infection (STI) Array
Silver Member
Compact 14-Day Uninterrupted Holter ECG
NR-314P
New
Silver Member
Mobile X-Ray Barrier
Lead Acrylic Mobile X-Ray Barriers

Print article

Channels

Surgical Techniques

view channel
Image: The Early Bird Bleed Monitoring System provides visual and audible indicators of the onset and progression of bleeding events (Photo courtesy of Saranas)

Novel Technology Monitors and Lowers Bleeding Complications in Patients Undergoing Heart Procedures

Bleeding complications at the femoral access site can significantly hamper recovery, affecting the success of procedures, patient satisfaction, and overall healthcare costs. It is crucial for surgeons... Read more

Patient Care

view channel
Image: The newly-launched solution can transform operating room scheduling and boost utilization rates (Photo courtesy of Fujitsu)

Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization

An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The new eye-safe laser technology can diagnose traumatic brain injury (Photo courtesy of 123RF)

Novel Diagnostic Hand-Held Device Detects Known Biomarkers for Traumatic Brain Injury

The growing need for prompt and efficient diagnosis of traumatic brain injury (TBI), a major cause of mortality globally, has spurred the development of innovative diagnostic technologies.... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.