We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Comen Medical

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
24 Jan 2022 - 27 Jan 2022

New Coating Reduces Catheter Pain and Infection Risk

By HospiMedica International staff writers
Posted on 18 Mar 2020
Print article
Image: Dr. Nicola Irwin applying the coating to a catheter (Photo courtesy of QUB)
Image: Dr. Nicola Irwin applying the coating to a catheter (Photo courtesy of QUB)
A new antimicrobial coating for urinary catheters and other medical devices can significantly reduce pain and risk of infection, according to a new study.

The coating, developed at Queen's University Belfast (QUB; United Kingdom) and the University of Leeds (United Kingdom), was created using a unique mix of polymers that reduce the coefficient of friction values in polyvinyl chloride (PVC) biomaterials by more than 300-fold, due to hydration of the surface-localized polymer network. To test the coating, the researchers created a clinically relevant model of the urinary tract in order to simulate the mechanical and biological environments encountered in vivo.

The researchers found that lubrication capacity was retained following hydration for periods lasting up to 28 days in artificial urine during 200 cycles of applied frictional force, both at a physiologically normal pH 6, and also at pH 9, which represents infected urine. The modified surfaces also demonstrated good antibacterial activity, achieving adherence reduction of 99.8% in common hospital-acquired pathogens, such as Staphylococcus aureus and Proteus mirabilis. The antibacterial activity was achieved by adding chlorhexidine into the coating matrix. The study was published on March 4, 2020, in ACS Applied Bio Materials.

“Patients with poor control over their bladder function, for example those with urinary retention or drainage problems caused by neurological conditions such as spina bifida or spinal cord injuries may need catheterization up to eight times a day,” said lead author Nicola Irwin, PhD, of QUB. “Insertion and removal of poorly lubricated catheters causes friction between the urethral walls and the device surface, which is not only extremely painful, but upon regular use can lead to damage and narrowing of the urethra, bleeding, and infection.”

“People who use medical devices such as catheters on a daily basis are at high risk of persistent low-level infections, which, overtime, can cause antibiotic resistance, one the biggest global threats to society today, leading to longer hospital stays, higher medical costs, and increased risk of infection and even death,” said study co-author Professor Colin McCoy, PhD, of QUB. “It is vitally important we provide an alternative to the currently used devices, which have not changed much since their introduction almost 100 years ago, despite their widespread clinical and many associated limitations.”

Related Links:
Queen's University Belfast
University of Leeds

Print article



view channel

J&J Medical Devices Companies Partners with Microsoft to Further Enable its Digital Surgery Solutions

The Johnson & Johnson Medical Devices Companies (JJMDC; New Brunswick, NJ, USA) will collaborate with Microsoft (Redmond, Wash., USA) to further enable and expand JJMDC’s secure and compliant digital... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.