Palm-Sized Sensor Detects Disease-Causing Microbes

The new-generation of self-contained analyzers relies on simpler components, in this case four pulse-powered light-emitting diodes (LEDs) that light up in specific patters to produce test results without a computer. The different emission spectra and reflected light beams from all LEDs are detected by a single photodiode.

Dr. Pavel Neuzil and Dr. Julien Reboud of the Institute of Microelectronics (Singapore Science Park II, Singapore) described a complete palm-sized, battery-operated biodetection system based on highly sensitive localized surface plasmon resonance (LSPR) in the July 1, 2008 online issue of the journal Analytical Chemistry. Surface plasmon resonance (SPR) has become a standard, label-free method for the detection of proteins and other biomolecules. It is based on the excitation of a surface plasmon at the interface between a dielectric and a thin layer of metal, typically gold.

Ideal for point-of-care diagnostics as well as for field detection of pathogens, even in remote areas, the analyzer also instantly detects toxins and other biologic threats.


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