We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Comen Medical

Medtronic

Medtronic offers medical products and therapies for the treatment of cardiac and vascular diseases, diabetes, and neu... read more Featured Products: More products

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Novel Transcatheter Heart Valve Alleviates CHD Symptoms

By HospiMedica International staff writers
Posted on 07 Apr 2021
Print article
Image: The Harmony TPV improves CHD patients’ quality of life (Photo courtesy of Medtronic)
Image: The Harmony TPV improves CHD patients’ quality of life (Photo courtesy of Medtronic)
A new transcatheter pulmonary valve (TPV) implant treats severe regurgitation in people who have not received a prior valve or right ventricle-pulmonary artery (RV-PA) conduit.

The Medtronic (Dublin, Ireland) Harmony TPV offers a treatment alternative for patients with congenital heart disease (CHD), specifically for those born with right ventricular outflow tract (RVOT) anomalies that require a less invasive option to restore normal valve function later in life. The Harmony is comprised of a porcine pericardium valve, sewn to a polyester-covered asymmetrical hourglass nitinol frame, thus providing natural venous valve leaflets that open and close under minimal pressure for optimal hemodynamics.

Harmony TPV placement is via a transcatheter procedure using a 25 Fr delivery system. During the implantation procedure, a catheter pre-loaded with a collapsed valve is inserted through a vein in the groin or in the neck and into the right side of the heart, and then into the RVOT where it is placed into position. The valve is then released from the catheter; it expands on its own, and anchors to the RVOT. Once the new valve is in place, it opens and closes like a door to force the blood to flow in the correct direction. Deep coaptation of the leaflets provides valve competency across a range of conduit sizes and geometries.

“The Harmony TPV provides a new treatment option for adult and pediatric patients with certain types of congenital heart disease,” said Bram Zuckerman, MD, of the FDA Center for Devices and Radiological Health (CDRH). “It offers a less-invasive treatment alternative to open-heart surgery to patients with a leaky native or surgically-repaired RVOT and may help patients improve their quality of life and return to their normal activities more quickly, thus fulfilling an unmet clinical need of many patients with congenital heart disease.”

TPV is an established method of treating pathologic regurgitation or stenosis of the pulmonary valve, RVOT, or RV-PA due to CHD defects such as Tetralogy of Fallot and pulmonary atresia. But despite excellent long-term survival, patients typically require multiple operative procedures until adulthood, as homograft pulmonary artery conduits or grafts have no ability to grow and remodel with the somatic growth of the child. Additionally, an intense inflammatory reaction to these materials commonly occurs, resulting in early calcification and failure.





Print article

Channels

Business

view channel
Image: Respicardia’s remedē System (Photo courtesy of Respicardia, Inc.)

Zoll Medical Acquires CSA Systems Manufacturer Respicardia

ZOLL Medical Corporation (Chelmsford, MA, USA), an Asahi Kasei company, has acquired Respicardia, Inc. (Minnetonka, MN, USA), a provider of novel implantable neurostimulators for the treatment of moderate... Read more
Copyright © 2000-2021 Globetech Media. All rights reserved.