We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Medtronic

Medtronic offers medical products and therapies for the treatment of cardiac and vascular diseases, diabetes, and neu... read more Featured Products: More products

Download Mobile App




Novel Transcatheter Heart Valve Alleviates CHD Symptoms

By HospiMedica International staff writers
Posted on 07 Apr 2021
Print article
Image: The Harmony TPV improves CHD patients’ quality of life (Photo courtesy of Medtronic)
Image: The Harmony TPV improves CHD patients’ quality of life (Photo courtesy of Medtronic)
A new transcatheter pulmonary valve (TPV) implant treats severe regurgitation in people who have not received a prior valve or right ventricle-pulmonary artery (RV-PA) conduit.

The Medtronic (Dublin, Ireland) Harmony TPV offers a treatment alternative for patients with congenital heart disease (CHD), specifically for those born with right ventricular outflow tract (RVOT) anomalies that require a less invasive option to restore normal valve function later in life. The Harmony is comprised of a porcine pericardium valve, sewn to a polyester-covered asymmetrical hourglass nitinol frame, thus providing natural venous valve leaflets that open and close under minimal pressure for optimal hemodynamics.

Harmony TPV placement is via a transcatheter procedure using a 25 Fr delivery system. During the implantation procedure, a catheter pre-loaded with a collapsed valve is inserted through a vein in the groin or in the neck and into the right side of the heart, and then into the RVOT where it is placed into position. The valve is then released from the catheter; it expands on its own, and anchors to the RVOT. Once the new valve is in place, it opens and closes like a door to force the blood to flow in the correct direction. Deep coaptation of the leaflets provides valve competency across a range of conduit sizes and geometries.

“The Harmony TPV provides a new treatment option for adult and pediatric patients with certain types of congenital heart disease,” said Bram Zuckerman, MD, of the FDA Center for Devices and Radiological Health (CDRH). “It offers a less-invasive treatment alternative to open-heart surgery to patients with a leaky native or surgically-repaired RVOT and may help patients improve their quality of life and return to their normal activities more quickly, thus fulfilling an unmet clinical need of many patients with congenital heart disease.”

TPV is an established method of treating pathologic regurgitation or stenosis of the pulmonary valve, RVOT, or RV-PA due to CHD defects such as Tetralogy of Fallot and pulmonary atresia. But despite excellent long-term survival, patients typically require multiple operative procedures until adulthood, as homograft pulmonary artery conduits or grafts have no ability to grow and remodel with the somatic growth of the child. Additionally, an intense inflammatory reaction to these materials commonly occurs, resulting in early calcification and failure.




Gold Member
Disposable Protective Suit For Medical Use
Disposable Protective Suit For Medical Use
Gold Member
Real-Time Diagnostics Onscreen Viewer
GEMweb Live
Silver Member
Compact 14-Day Uninterrupted Holter ECG
NR-314P
New
PACS Workstation
CHILI Web Viewer

Print article

Channels

Critical Care

view channel
Image: Researchers have developed a novel risk score for cardiovascular complications after bone marrow transplant (Photo courtesy of 123RF)

Novel Tool Predicts Cardiovascular Risks after Bone Marrow Transplantation

Every year, thousands of people undergo bone marrow transplants to potentially cure serious diseases like leukemia, lymphoma, and immune deficiency disorders. While these transplants can be lifesaving,... Read more

Patient Care

view channel
Image: The newly-launched solution can transform operating room scheduling and boost utilization rates (Photo courtesy of Fujitsu)

Surgical Capacity Optimization Solution Helps Hospitals Boost OR Utilization

An innovative solution has the capability to transform surgical capacity utilization by targeting the root cause of surgical block time inefficiencies. Fujitsu Limited’s (Tokyo, Japan) Surgical Capacity... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: The new eye-safe laser technology can diagnose traumatic brain injury (Photo courtesy of 123RF)

Novel Diagnostic Hand-Held Device Detects Known Biomarkers for Traumatic Brain Injury

The growing need for prompt and efficient diagnosis of traumatic brain injury (TBI), a major cause of mortality globally, has spurred the development of innovative diagnostic technologies.... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.