We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress hp
Sign In
Advertise with Us

Download Mobile App


31 Jul 2024 - 02 Aug 2024
02 Aug 2024 - 04 Aug 2024
20 Aug 2024 - 22 Aug 2024

Nano-Thin Superbug-Slaying Material Integrated into Implants Can Prevent or Heal Bacterial Infections

By HospiMedica International staff writers
Posted on 15 Sep 2023
Print article
Image: The ball shapes are bacteria and the “sheet” is black phosphorus, as seen under a microscope (Photo courtesy of RMIT University)
Image: The ball shapes are bacteria and the “sheet” is black phosphorus, as seen under a microscope (Photo courtesy of RMIT University)

Antibiotic resistance is turning into a severe worldwide health crisis, contributing to approximately 700,000 deaths each year. This number could skyrocket to 10 million annual deaths by 2050 if new antibacterial treatments aren't developed. Superbugs, the culprits behind the huge health burdens, are bacteria that have grown resistant to antibiotics. As their resistance increases, it's becoming exceedingly difficult to manage and treat infections caused by these pathogens. Medical professionals globally are urgently seeking alternative ways to treat bacterial infections without relying on antibiotics. Now, researchers have invented a nano-thin superbug-eliminating material that can be used in wound dressings and implants to either prevent or treat bacterial infections.

Black phosphorus is the most stable form of phosphorus, a naturally occurring mineral found in numerous foods. In its ultra-thin form, black phosphorus easily degrades upon contact with oxygen, making it a potent microbe killer. A previous study led by researchers at RMIT University (Melbourne, VC, Australia) had found that when black phosphorus was used in nano-thin coatings on materials like cotton and titanium—common in wound dressings and implants—it effectively killed microbes. Their latest study examined how well this black phosphorus-based nanotechnology could perform in advanced infection treatments and wound healing.

The study found the treatment to be extremely effective, killing more than 99% of bacteria while sparing other cells in biological models. It achieved results comparable to antibiotics in wiping out infections and even promoted quicker wound healing, with wounds showing 80% closure within a week. The superbug-killing nanotechnology by RMIT exhibited rapid antimicrobial action and then self-decomposed after the infection risk was eliminated. It proved effective against a wide spectrum of antibiotic-resistant bacteria, including strains like 'golden staph,' commonly classified as superbugs. RMIT has moved to patent this innovative use of black phosphorus flakes, particularly its applications in wound healing products like gels.

“This is exciting as the treatment was comparable to the ciprofloxacin antibiotic in eradicating wound infection and resulted in accelerated healing, with wounds closing by 80% over seven days,” said lead researcher, Dr. Zlatko Kopecki. “We urgently need to develop new alternative non-antibiotic approaches to treat and manage wound infection. Black phosphorus seems to have hit the spot and we look forward to seeing the translation of this research towards clinical treatment of chronic wounds.”

Related Links:
RMIT University 

Gold Member
12-Channel ECG
Gold Member
Real-Time Diagnostics Onscreen Viewer
GEMweb Live
Silver Member
Compact 14-Day Uninterrupted Holter ECG
Folding Portering Chair

Print article


Surgical Techniques

view channel
Image: Electronic prompt for surgeons may reduce breast cancer overtreatment (Photo courtesy of 123RF)

EHR–Based Nudge Intervention for Surgeons to Reduce Breast Cancer Overtreatment

Sentinel lymph node biopsy (SLNB) is a critical surgical technique used to assess if breast cancer has spread to the underarm lymph nodes, although it's not necessary for all patients. Undergoing SLNB... Read more

Patient Care

view channel
Image: The portable, handheld BeamClean technology inactivates pathogens on commonly touched surfaces in seconds (Photo courtesy of Freestyle Partners)

First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds

Reducing healthcare-acquired infections (HAIs) remains a pressing issue within global healthcare systems. In the United States alone, 1.7 million patients contract HAIs annually, leading to approximately... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: POCT offers cost-effective, accessible, and immediate diagnostic solutions (Photo courtesy of Flinders University)

POCT for Infectious Diseases Delivers Laboratory Equivalent Pathology Results

On-site pathology tests for infectious diseases in rural and remote locations can achieve the same level of reliability and accuracy as those conducted in hospital laboratories, a recent study suggests.... Read more


view channel
Image: The Innovalve transseptal delivery system is designed to enable safe deployment of the Innovalve implant (Photo courtesy of Innovalve Bio)

Edwards Lifesciences Acquires Sheba Medical’s Innovalve Bio Medical

Edwards Lifesciences (Irvine, CA, USA), a leading company in medical innovations for structural heart disease and critical care, has acquired Innovalve Bio Medical LTD. (Ramat Gan, Israel), an early-stage... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.