We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Thermo Fisher Scientific - Direct Effect Media

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Positive Blood Culture Processing Technology Accelerates Infection Identification and AST

By HospiMedica International staff writers
Posted on 26 Apr 2022
Print article
Image: The FAST System runs the FAST-PBC Prep Cartridges (Photo courtesy of Qvella)
Image: The FAST System runs the FAST-PBC Prep Cartridges (Photo courtesy of Qvella)

Sepsis is the most deadly and costly hospital condition to treat. 80% of sepsis deaths could be prevented with rapid diagnosis and treatment, although diagnosis today is a multi-step process that takes 1 to 5 days to pathogen ID and appropriate or optimal antimicrobial therapy. Moreover, 30%-45% of sepsis patients receive inappropriate initial antimicrobial therapy and every hour delay of appropriate antimicrobial treatment increases morbidity and mortality associated with sepsis. Now, a new system has the potential to expedite ID and AST for blood-borne pathogens from positive blood cultures.

Qvella’s (Richmond Hill, ON, Canada) AST System and FAST-PBC Prep Cartridge product for Positive Blood Culture (PBC) processing uses its patented FAST-Technology (Field Activated Sample Treatment) to eliminate the need for time-consuming culture methods. This allows the processing of downstream applications up to 24 hours faster than current methods so lifesaving treatment, for example, could be started much more quickly than ever before. This disruptive technology can change outcomes for patients, while simultaneously saving money for healthcare providers.

The FAST System isolates and concentrates pathogens to generate a Liquid Colony (LC) which can be readily used to set up for a variety of downstream workflows, including ID by MALDI-TOF, and AST by automated systems such as BD Phoenix, bioMérieux VITEK2, Beckman Coulter MicroScan WalkAway, Disc Diffusion, and others. The resulting LC very closely match the standard of care. The LC can be generated immediately after obtaining a PBC, potentially saving 24 hours or more in diagnosis of infections.

Recent beta trials of Qvella’s FAST System and FAST-PBC Prep Cartridge have shown that Qvella’s technology easily integrates with existing workflows, and the fully automated solution requires a minimal hands-on time of approximately two minutes. Qvella has announced the commercialization of its FAST System and FAST-PBC Prep Cartridge product for PBC processing. The products have received CE marking for in vitro diagnostic (IVD) use in Europe and are now listed as Class I IVD devices with the FDA for the U.S. market.

“With several performance evaluation studies completed and EU and USA marketing authorization granted, we have officially reached the commercialization milestone for our FAST System,” said Tino Alavie, president, CEO, and co-founder of Qvella. “Given the shortage of technicians that healthcare systems are seeing right now amid the COVID-19 pandemic, the timing could not be better for the commercialization of our technology. It can be used to accelerate infection identification, for example, or to accelerate antibiotic susceptibility testing, with results delivered 24 hours earlier than previously possible. It is also very cost effective compared to molecular blood culture identification panels.”

Related Links:

Print article


Critical Care

view channel
Image: Triage Cardiac Panel is a rapid, POC fluorescence immunoassay used with Triage MeterPro (Photo courtesy of Quidel)

Quidel Triage Cardiac Panel Facilitates Rapid POC Diagnosis of Chest Pain Patients in ED

Chest and abdominal pain are the most common reasons that persons aged 15 years and over visit the emergency department (ED). Because both emergency and non-emergency care are provided, symptoms vary widely... Read more

Surgical Techniques

view channel
Image: A minimally invasive diagnostic biomarker strategy has proven successful in detecting early esophageal cancer (Photo courtesy of Pexels)

Minimally Invasive Device Combined With Molecular Biomarkers Detects Early Esophageal Cancer

Esophageal cancer remains the sixth-most common cause of cancer death worldwide, claiming the lives of more than half a million people annually. Esophageal squamous cell carcinoma (ESCC) comprises 80%... Read more

Patient Care

view channel
Image: Future wearable health tech could measure gases released from skin (Photo courtesy of Pexels)

Wearable Health Tech Could Measure Gases Released From Skin to Monitor Metabolic Diseases

Most research on measuring human biomarkers, which are measures of a body’s health, rely on electrical signals to sense the chemicals excreted in sweat. But sensors that rely on perspiration often require... Read more

Health IT

view channel
Image: AI can reveal a patient`s heart health (Photo courtesy of Mayo Clinic)

AI Trained for Specific Vocal Biomarkers Could Accurately Predict Coronary Artery Disease

Earlier studies have examined the use of voice analysis for identifying voice markers associated with coronary artery disease (CAD) and heart failure. Other research groups have explored the use of similar... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.