We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Thermo Fisher Scientific - Direct Effect Media

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Novel Biomaterial Aids Post-Surgical Heart Reconstruction

By HospiMedica International staff writers
Posted on 19 Jan 2022
Print article
Image: The CardiaMend pericardial and epicardial reconstruction matrix (Photo courtesy of helios cardio)
Image: The CardiaMend pericardial and epicardial reconstruction matrix (Photo courtesy of helios cardio)
An ultra-pure, collagen rich biological matrix assists pericardial repair and reconstruction and epicardial support and repair following cardiac surgery.

The helios cardio (Westin, MA, USA) CardiaMend Pericardial and Epicardial reconstruction matrix is a porous acellular matrix derived from fetal bovine dermis (EBM), providing soft tissue reinforcement, repair, and reconstruction. The single-ply EBM matrix consists of a natural woven network of type III collagen fibers that provide a hospitable micro-environment for cardiac cells, which can recognize collagen fiber orientation, incorporated structural proteins, sequestered paracrine factors, pore size, and many other components.

Progenitor cells and nutrients finding their way extracellular matrix (ECM) surrounding the matrix then differentiate into tissue-specific cells and structures. CardiaMend reconstruction EBM, which is not chemically crosslinked, is then gradually and naturally degraded and resorbed, replaced by the patient’s own cells, leaving behind a remodeled, functional tissue. CardiaMend is supplied terminally sterilized--via ethylene oxide vapor--and is available in a variety of sizes and thicknesses that can be trimmed by the physician to meet individual patient needs.

“We are looking forward to providing cardiac surgeons with the strongest and most regenerative biologic implant available to date,” said Yiannis Monovoukas, PhD, CEO of Helios Cardio. “Our intention, however, is not to stop there, but to further extend the functionality of CardiaMend towards true cardiac tissue regeneration, and to achieve our ultimate goal of mending broken hearts.”

The ECM is a collection of extracellular molecules that provides structural and biochemical support to the surrounding cells. It includes the interstitial matrix, composed of polysaccharide gels and fibrous proteins, and the basement membrane, which are sheet-like depositions on which various epithelial cells rest. Each type of connective tissue in animals has a different ECM; collagen fibers and bone mineral comprise the ECM of bone tissue; reticular fibers and ground substance comprise the ECM of loose connective tissue; and blood plasma is the ECM of blood.

Related Links:
helios cardio


Print article

Channels

Critical Care

view channel
Image: EsoGuard has demonstrated over 90% specificity and 90% sensitivity in identifying Barrett’s Esophagus (Photo courtesy of Lucid Diagnostics)

Biomarker Based Non-Endoscopic Technology Identifies Risk for Esophageal Cancer

Barrett's esophagus (BE) is the benign and treatable precursor condition to esophageal adenocarcinomas (EAC) which is usually diagnosed at an advanced stage and is difficult to treat. Finding BE, a sign... Read more

Patient Care

view channel
Image: Future wearable health tech could measure gases released from skin (Photo courtesy of Pexels)

Wearable Health Tech Could Measure Gases Released From Skin to Monitor Metabolic Diseases

Most research on measuring human biomarkers, which are measures of a body’s health, rely on electrical signals to sense the chemicals excreted in sweat. But sensors that rely on perspiration often require... Read more

Health IT

view channel
Image: AI can reveal a patient`s heart health (Photo courtesy of Mayo Clinic)

AI Trained for Specific Vocal Biomarkers Could Accurately Predict Coronary Artery Disease

Earlier studies have examined the use of voice analysis for identifying voice markers associated with coronary artery disease (CAD) and heart failure. Other research groups have explored the use of similar... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.