We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Thermo Fisher Scientific - Direct Effect Media

Download Mobile App




Events

ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Woven EndoBridge (WEB) Device Found Effective in Treating Sidewall Brain Aneurysm

By HospiMedica International staff writers
Posted on 20 Apr 2022
Print article
Image: Novel treatment effective for sidewall brain aneurysm (Photo courtesy of Unsplash)
Image: Novel treatment effective for sidewall brain aneurysm (Photo courtesy of Unsplash)

A braided wire device known as the Woven EndoBridge (WEB) that has been approved by the U.S. Food and Drug Administration (FDA) for wide-neck intracranial bifurcation aneurysms has also been used off-label by some specialists for the treatment of sidewall aneurysms. Research on the WEB device's use in wide-necked sidewall aneurysms has been limited to studies with a small number of cases. Now, a new study has found that the novel mesh plug that has been traditionally used to treat brain aneurysms occurring where the blood vessels branch out can be equally effective in treating aneurysms on the side of the vessel.

The new study conducted by researchers at the Louisiana State University (Shreveport, LA, USA) will help drive a discussion about expanding the indications for the WEB device to include certain sidewall aneurysms. Aneurysms result from a weakness in the blood vessel wall that typically occurs where the vessel branches or bifurcates—where the vessel divides or forks into two branches. Untreated, an aneurysm can grow and rupture. A common treatment involving the placement of tiny platinum coils into the aneurysm has limitations. The WEB device was developed to overcome those limitations. The device is placed inside the aneurysm under angiographic guidance, where it causes a clot to form, closing off the aneurysm and reducing the risk of bleeding without requiring supporting stents or blood thinners. Sidewall aneurysms are a type of wide-necked aneurysm that occurs at the side of a blood vessel rather than its bifurcation tip.

For the new study, the researchers compared the WEB device in bifurcation and sidewall aneurysms using a large database spanning more than 10 years from the WorldWideWEB consortium, a group of 23 academic institutions in North America, South America, Australia and Europe. A total of 683 intracranial aneurysms were treated using the WEB device in 671 patients. Of those, 572 were bifurcation aneurysms, and 111 were sidewall aneurysms. Propensity score matching, a way to increase the power of a study by accounting for differences in patients, resulted in 91 bifurcation and sidewall aneurysms pairs. The complication rate was very similar between the two approaches. The researchers are continuing the research comparing the WEB device with other treatments for different types and locations of aneurysms. They also plan to track changes that happen to device shape and compaction over time and its relationship to aneurysm occlusion status.

"We found out that there is no significant difference using the WEB device in sidewall aneurysms compared with bifurcation aneurysms," said study lead author Nimer Adeeb, M.D., from the Department of Neurosurgery and Interventional Neuroradiology at Louisiana State University. "The results show that the WEB device is safe and effective to use for sidewall aneurysms."

Related Links:
Louisiana State University 


Print article

Channels

Critical Care

view channel
Image: Triage Cardiac Panel is a rapid, POC fluorescence immunoassay used with Triage MeterPro (Photo courtesy of Quidel)

Quidel Triage Cardiac Panel Facilitates Rapid POC Diagnosis of Chest Pain Patients in ED

Chest and abdominal pain are the most common reasons that persons aged 15 years and over visit the emergency department (ED). Because both emergency and non-emergency care are provided, symptoms vary widely... Read more

Patient Care

view channel
Image: Future wearable health tech could measure gases released from skin (Photo courtesy of Pexels)

Wearable Health Tech Could Measure Gases Released From Skin to Monitor Metabolic Diseases

Most research on measuring human biomarkers, which are measures of a body’s health, rely on electrical signals to sense the chemicals excreted in sweat. But sensors that rely on perspiration often require... Read more

Health IT

view channel
Image: AI can reveal a patient`s heart health (Photo courtesy of Mayo Clinic)

AI Trained for Specific Vocal Biomarkers Could Accurately Predict Coronary Artery Disease

Earlier studies have examined the use of voice analysis for identifying voice markers associated with coronary artery disease (CAD) and heart failure. Other research groups have explored the use of similar... Read more
Copyright © 2000-2022 Globetech Media. All rights reserved.