We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us

Download Mobile App


ATTENTION: Due to the COVID-19 PANDEMIC, many events are being rescheduled for a later date, converted into virtual venues, or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.

Bio-Expandable Bone Graft Could Help Spinal Surgery Patients

By HospiMedica International staff writers
Posted on 13 Apr 2016
Print article
Image: Expanding polymer bone graft to replace excised spinal tissue (Photo courtesy of Dr. Lichin Lu).
Image: Expanding polymer bone graft to replace excised spinal tissue (Photo courtesy of Dr. Lichin Lu).
An expandable, biodegradable graft could help metastatic spinal tumor patients recover from the surgical removal of bone segments and intervertebral discs, according to a new study.

Researchers at the Mayo Clinic (Rochester, MN, USA) have developed a biodegradable, hydrophilic, polymer graft that when surgically placed in the damaged vertebrae, expands to precisely fill the resected areas by absorbing bodily fluids. The graft is composed of two sections; a hollow hydrophilic scaffold made of crosslinked oligo(poly(ethylene glycol) fumarate) (OPF), and a stabilized polymer filler material. To develop the graft, the researchers first identified a combination of materials that are biocompatible in animals, and which they believe will work in humans.

To control the kinetics of the polymer graft expansion, the researchers made chemical changes to the filler to modify the degree and timing of the expansion, under conditions that mimicked the spinal column environment. The modulation of the molecular weight and charge of the polymer enabled them to tune the material’s properties so that the expansion rate was slow enough to enable surgeons to place it correctly, but fast enough so that it did not extend surgery times. The study was presented at the 251st national meeting & exposition of the American Chemical Society (ACS), held during March 2016 in San Diego (CA, USA).

“The overall goal of this research is to find ways to treat people with metastatic spinal tumors; the spine is the most common site of skeletal metastases in cancer patients, but unlike current treatments, our approach is less invasive and is inexpensive,” said lead author and study presenter Lichun Lu, PhD. “When we designed this expandable tube, we wanted to be able to control the size of the graft so it would fit into the exact space left behind after removing the tumor.”

Related Links:

Mayo Clinic

Gold Supplier
12-Channel ECG
Wound Dressing
Thin Absorbent Wound Dressing Featuring TASA
Mobile X-Ray Table
X Mobil
High-Frequency X-Ray Generator
Battery X-Ray Generator

Print article
FIME - Informa



view channel
Image: The AI tool can also tackle dangerous inequalities in heart attack diagnosis (Photo courtesy of Freepik)

AI Algorithm Integrates Cardiac Troponin Test Results with Clinical Data to Quickly Rule out Heart Attacks in Patients

The accepted standard for diagnosing myocardial infarction, or heart attack, involves assessing the blood for troponin levels. However, this approach applies the same benchmark for all patients, failing... Read more

Critical Care

view channel
Image: Electromagnetic cores precisely guide the array of nanozyme-bots as they target the site of fungal infection (Photo courtesy of University of Pennsylvania)

Nanorobots Guided by Magnets Capable of Rapid, Targeted Elimination of Fungal Pathogens

Fungal infections, particularly those caused by Candida albicans, present a significant health threat globally due to their resistance to current treatments. Although nanomaterials show potential as antifungal... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: IntelliSep is the first FDA-cleared diagnostic tool to assess cellular host response to aid in identifying ED patients with sepsis (Photo courtesy of Cytovale)

Rapid Microfluidic Test Demonstrates Efficacy as Diagnostic Aid to Improve Sepsis Triage in ED

Sepsis is the primary cause of mortality worldwide, accounting for over 350,000 fatalities annually in the United States alone, a figure that surpasses deaths from opioid overdoses, prostate cancer, and... Read more
Copyright © 2000-2023 Globetech Media. All rights reserved.