We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Ampronix,  Inc

Download Mobile App




Events

ATTENTION: Due to the CORONAVIRUS EPIDEMIC, certain events are being rescheduled for a later date or altogether cancelled. Please check with the event organizer or website prior to planning for any forthcoming event.
06 May 2020 - 09 May 2020

Conjugated Prosthesis Treats Aortic Root Disease

By HospiMedica International staff writers
Posted on 10 Mar 2020
Print article
Image: The On-X AAP prosthesis treats ascending aortic aneurysms (Photo courtesy of On-X Life Technologies)
Image: The On-X AAP prosthesis treats ascending aortic aneurysms (Photo courtesy of On-X Life Technologies)
An ascending aortic prosthesis (AAP) helps treat diseased, damaged, or malfunctioning native or prosthetic heart valves involved in an ascending aortic aneurysm.

The CryoLife (Kennesaw, GA, USA) On-X AAP combines the company’s On-X prosthetic heart valve and the Gelweave Valsalva vascular prosthesis, which is integrated into the cuff structure of the On-X prosthetic heart valve in order to create the AAP. The On-X prosthetic heart valve itself is a bileaflet mechanical heart valve with an orifice and two leaflets. In the closed position, each leaflet forms a nominal angle of 40º relative to the plane of the orifice. In the open position, each leaflet forms a nominal angle of 90º relative to the plane of the orifice. The orifice inflow area has a flared inlet designed to reduce flow turbulence.

The second component of the AAP, the Gelweave Valsalva vascular prosthesis is a woven polyester prosthesis designed to mimic the geometry of the sinus of Valsalva. The graft is impregnated with an absorbable modified mammalian gelatin in order to eliminate pre-clotting of the graft in surgery. After implantation, the gelatin is hydrolyzed within approximately 14 days and is then replaced by normal tissue.

The orifice itself is composed of a graphite substrate coated with On-X Carbon, a pure unalloyed form of pyrolytic carbon. The leaflets consist of On-X Carbon deposited on graphite substrates impregnated with 10% tungsten to provide radiopacity. The sewing cuff is made of polytetrafluoroethylene (PTFE) fabric mounted on the orifice using titanium retaining rings and 5-0 polyester suture material. This form of sewing cuff attachment to the orifice allows for rotation of the sewing cuff in situ during implantation. The AAP prosthesis is available in sizes 19, 21, 23, 25, and 27/29 mm.

An AAP is an enlargement of a weakened area in the ascending aorta. While other aneurysms of the aorta are associated with atherosclerosis, aneurysms of the ascending aorta are mostly associated with degenerative elastic fiber fragmentation and smooth muscle loss in the medial layer of the blood vessel wall. The aortic wall then loses its strength and elasticity, becoming aneurysmal, and may then dissect or rupture.

Related Links:
CryoLife


Print article

Channels

Business

view channel
Illustration

Surgical Robots Market to Reach USD 13.1 Billion by 2027 Due to High Acceptance in Emerging Regions

The global surgical robots market is forecasted to reach USD 13.1 billion by 2027, driven mainly by low turn-around times and increased innovation in robotics over the coming years. Surgical robots are... Read more
Copyright © 2000-2020 Globetech Media. All rights reserved.