We use cookies to understand how you use our site and to improve your experience. This includes personalizing content and advertising. To learn more, click here. By continuing to use our site, you accept our use of cookies. Cookie Policy.

Features Partner Sites Information LinkXpress
Sign In
Advertise with Us
Sekisui Diagnostics UK Ltd.

Download Mobile App

Transcatheter Valve Replacement Outcomes Similar To Surgery, Finds Study

By HospiMedica International staff writers
Posted on 21 May 2024
Print article
Image: The largest scale analysis compared longer-term percutaneous devices for aortic valve replacement versus surgery (Photo courtesy of Adobe Stock)
Image: The largest scale analysis compared longer-term percutaneous devices for aortic valve replacement versus surgery (Photo courtesy of Adobe Stock)

A new study has shown that a minimally invasive procedure for replacing the aortic valve in the heart—known as transcatheter aortic valve replacement (TAVR)—is on par with the more traditional surgical aortic valve replacement (SAVR).

In a meta-analysis conducted by researchers at the University of Sassari (Sassari, Italy), they evaluated seven randomized trials involving 7,785 patients who underwent TAVR—a procedure that introduces a new aortic valve via a catheter—or SAVR for severe aortic stenosis. The findings revealed no significant differences in the rates of death or disabling stroke between the TAVR and SAVR groups, with both showing similar long-term mortality risks. These results held true across various surgical risk profiles, including low, intermediate, and high risk. However, compared to SAVR, TAVR was linked to a higher likelihood of requiring a pacemaker and experiencing moderate-to-severe paravalvular leaks.

Furthermore, the study conducted a prespecified analysis comparing the outcomes associated with two different types of TAVR devices against SAVR. This analysis found that, relative to SAVR, self-expanding TAVR prostheses had a lower risk of death or stroke, valve thrombosis, and valve gradients, but a higher rate of pacemaker implantation compared to balloon-expandable TAVR devices, underscoring potential long-term differences between these two percutaneous TAVR options.

“This study represents the largest scale analysis so far available comparing longer-term percutaneous devices for aortic valve replacement versus surgery,” said study coauthor Eliano Pio Navarese, MD, PhD, head of clinical experimental cardiology and associate professor at the University of Sassari. “Our findings support the comparable long-term safety and efficacy of TAVR, as well as raise important considerations for valve type selection, particularly when we are dealing with longer-term valve durability and pacemaker implantation.”

Related Links:
University of Sassari

Print article


Surgical Techniques

view channel
Image: Robotics and AI combination has potential to improve safety in emergency stroke surgeries (Photo courtesy of KCL)

Robotics Combined with AI Improves Safety in Emergency Stroke Surgeries

Cardiovascular diseases remain the leading cause of death throughout Europe, resulting in over 4 million fatalities annually. Mechanical thrombectomies (MT), which involve the surgical removal of blood... Read more

Patient Care

view channel
Image: The portable, handheld BeamClean technology inactivates pathogens on commonly touched surfaces in seconds (Photo courtesy of Freestyle Partners)

First-Of-Its-Kind Portable Germicidal Light Technology Disinfects High-Touch Clinical Surfaces in Seconds

Reducing healthcare-acquired infections (HAIs) remains a pressing issue within global healthcare systems. In the United States alone, 1.7 million patients contract HAIs annually, leading to approximately... Read more

Health IT

view channel
Image: First ever institution-specific model provides significant performance advantage over current population-derived models (Photo courtesy of Mount Sinai)

Machine Learning Model Improves Mortality Risk Prediction for Cardiac Surgery Patients

Machine learning algorithms have been deployed to create predictive models in various medical fields, with some demonstrating improved outcomes compared to their standard-of-care counterparts.... Read more

Point of Care

view channel
Image: POCT offers cost-effective, accessible, and immediate diagnostic solutions (Photo courtesy of Flinders University)

POCT for Infectious Diseases Delivers Laboratory Equivalent Pathology Results

On-site pathology tests for infectious diseases in rural and remote locations can achieve the same level of reliability and accuracy as those conducted in hospital laboratories, a recent study suggests.... Read more
Copyright © 2000-2024 Globetech Media. All rights reserved.