Ultraflexible, Gas-Permeable Thermistors to Pave Way for On-Skin Medical Sensors and Implantable Devices

In addition, the technology has to withstand bending and stretching, and it needs to be gas-permeable to prevent irritation and discomfort. Another important safety feature of these devices is the required overheat protection circuit. This prevents the devices from overheating and burning the wearer. Any new technology developed for these sensors must meet these needs. Now, researchers have demonstrated how an important component of the sensors called a thermistor can be constructed using an ultrathin fiber-mesh, paving the way for ultraflexible and gas-permeable thermistors that can act as overheat prevention components for on-skin or implantable devices.

Thermistors are a type of resistor whose resistance significantly varies with temperature. For such thermistors to be applied for on-skin medical sensors, they must be stretchable and bendable down to several hundred micrometers. It is important for this technology to be able to wrap around a needle because sometimes sensors are attached to needles or catheters while in use. In order to achieve this, the thermistor needs to be ultrathin. Researchers at Shinshu University (Matsumoto, Japan) used a technique called electrospinning to create the ultrathin mesh-type polymer PTC thermistor. Electrospinning uses electricity to create tiny fibers. The fibers can be made out of different materials, but in this case, researchers used a solution of composite materials.

The newly designed thermistor was then tested to ensure it achieved similar performance capabilities of existing technology. Like typical film-type thermistors, the mesh-type polymer PTC thermistor showed an increase in resistance of three orders of magnitude, an important characteristic for preventing overheating and burns. By using a mesh structure, the thermistor also achieved transparency, which can help the sensors blend into the skin, and gas-permeability. Gas-permeability is necessary because it prevents irritation and discomfort. Even with this fiber layer, which serves to give the mesh structure and additional heat sensing, the thermistor remained very thin. This is important because any wearable medical device must be able to withstand bending and when the device is thinner, there is less strain.

Though this thermistor technology is promising, more research will need to be done to make this a reliable alternative to the current thermistor technology on the market. A mesh-type thermistor has a high initial resistance value due to its limited number of conductive paths. The researchers proposed that reducing the spacing between fibers in the mesh or increasing the number of electrodes used could resolve some of these problems, but additional testing will need to be done.

“An overheat protection circuit is required to avoid burning biological tissues during the operation of flexible devices. One candidate is a polymer positive temperature coefficient (PTC) thermistor, which has a large increase in resistance within a narrow temperature range,” said Chihiro Okutani, an assistant professor in the Department of Electrical and Computer Engineering at Shinshu University in Japan. “For such thermistors to be applied for on-skin medical sensors, they must be stretchable and bendable down to several hundred micrometers. However, it is still challenging to fabricate a thermistor whose temperature characteristics do not deteriorate when wrapped around a needle with a bending radius of less than 1 mm.”

“We also demonstrated the operation of the thermistor wrapped around a 280-micrometer needle by fabricating the fibers on a 1.4 micrometer ultrathin film,” added Okutani. “Our next step is practical applications of the developed thermistors. We believe that the ultraflexible and gas-permeable thermistors can act as overheat prevention components for on-skin or implantable devices, which make flexible sensors safer to operate and more reliable.”

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Shinshu University